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|Title:||Pharmaceutical formulation and its use|
|Abstract:||The invention relates to a pharmaceutical formulation containing tolterodine or a tolterodine-related compound, or a pharmacologically acceptable salt thereof, as active ingredient, in which the formulation exhibits a controlled in vitro release of the active ingredient in phosphate buffer at pH 6.8 of not less than about 80% after 18 hours, and after oral administration to a patient is capable of maintaining a substantially constant serum level of the active moiety or moieties for 24 hours. The invention also relates to the use of the pharmaceutical formulation for treating overactive bladder and gastrointestinal disorders.|
|Inventor(s):||Nilvebrant; Lisbeth (Bromma, SE), Hallen; Bengt (Sollentuna, SE), Olsson; Birgitta (Stenhamra, SE), Strombom; Jan (Vattholm, SE), Gren; Torkek (Kalamazoo, MI), Ringberg; Anders (Stockholm, SE), Wikberg; Martin (Kullavik, SE)|
|Assignee:||Pharmacia AB (Stockholm, SE)|
Patent Claim Types:|
see list of patent claims
|Formulation; Compound; Dosage form; Use;|
Back Citations: 5th percentile
Forward Citations: 2nd percentile
|Applicant||Tradename||Generic Name||Dosage||NDA||Approval Date||Type||RLD||Patent No.||Patent Expiration||Product||Substance||Delist Req.||Patented / Exclusive Use|
Pharmacia And Upjohn
|CAPSULE, EXTENDED RELEASE;ORAL||021228-001||Dec 22, 2000||RX||No||6,630,162*PED||► subscribe||Y|
Pharmacia And Upjohn
|CAPSULE, EXTENDED RELEASE;ORAL||021228-002||Dec 22, 2000||RX||Yes||6,630,162*PED||► subscribe||Y|
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|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|Sweden||0000782||Mar 09, 2000|
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