Details for Patent: 6,596,316
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Summary for Patent: 6,596,316
Title: | Preparation of microparticles having a selected release profile |
Abstract: | An improved method for preparing microparticles that exhibit controlled release of an effective amount of an active agent over an extended period of time. More particularly, a method is provided for preparing microparticles having a selected release profile for release of active agent contained in the microparticles. By adjusting the degree of drying that is performed during the preparation of the microparticles, the release profile can be controlled. By performing no intermediate drying, an initial burst and a substantially linear release profile is achieved. By performing substantially complete intermediate drying, an initial lag phase and a substantially sigmoidal release profile is achieved. |
Inventor(s): | Lyons; Shawn L. (Cincinnati, OH), Ramstack; J. Michael (Lebanon, OH), Wright; Steven G. (Madeira, OH) |
Assignee: | Alkermes Controlled Therapeutics, Inc. II (Cambridge, MA) |
Application Number: | 10/059,115 |
Patent Claim Types: see list of patent claims | Process; Use; |
Drugs Protected by US Patent 6,596,316
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International Family Members for US Patent 6,596,316
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Austria | 308977 | ⤷ Try a Trial | |||
Australia | 3117800 | ⤷ Try a Trial | |||
Australia | 759214 | ⤷ Try a Trial | |||
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