Last Updated: August 8, 2026

Details for Patent: 6,525,057

Name: Drug Patent Intelligence for US Patent 6525057
Creator: DrugPatentWatch
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Summary for Patent: 6,525,057

Title:	Sustained release ranolazine formulations
Abstract:	A sustained release ranolazine formulation contains an intimate mixture of ranolazine and a partially neutralized pH-dependent binder to form a film that is mostly insoluble in aqueous media below pH 4.5 and soluble in aqueous media above pH 4.5. The formulation is suitable for twice daily administration of ranolazine and is useful for controlling the rate of dissolution of ranolazine, and to maintain human plasma ranolazine levels at between 550 and 7500 ng base/mL.
Inventor(s):	Andrew A. Wolff, Fiona Baker, John Langridge
Assignee:	Gilead Sciences Inc , Gilead Palo Alto Inc
Application Number:	US09/925,871
Patent Claim Types: see list of patent claims	Use; Composition; Formulation; Dosage form;

Drugs Protected by US Patent 6,525,057

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 6,525,057

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	1109558	⤷ Start Trial	PA2008017	Lithuania	⤷ Start Trial
European Patent Office	1109558	⤷ Start Trial	CA 2008 00051	Denmark	⤷ Start Trial
European Patent Office	1109558	⤷ Start Trial	91504	Luxembourg	⤷ Start Trial
European Patent Office	1109558	⤷ Start Trial	PA2008017,C1109558	Lithuania	⤷ Start Trial
European Patent Office	1109558	⤷ Start Trial	09C0001	France	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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