Last Updated: September 24, 2026

Details for Patent: 6,489,346

Name: Drug Patent Intelligence for US Patent 6489346
Creator: DrugPatentWatch
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Summary for Patent: 6,489,346

Title:	Substituted benzimidazole dosage forms and method of using same
Abstract:	There is provided a solid pharmaceutical composition in a dosage form that is not enteric-coated, having active ingredients including a non-enteric coated proton pump inhibitor and at least one buffering agent. The proton pump inhibitor is omeprazole, lansoprazole, rabeprazole, esomeprazole, pantoprazole, pariprazole, and leminoprazole, or an enantiomer, isomer, derivative, free base, or salt thereof, in an amount of approximately 5 mg to approximately 300 mg; and the buffering agent is in an amount of approximately 0.1 mEq to approximately 2.5 mEq per mg of proton pump inhibitor. The dosage form includes a suspension tablet, a chewable tablet, an effervescent powder, or an effervescent tablet. Also provided is a method for treating an acid-related gastrointestinal disorder in a subject in need thereof by administering to the subject a solid pharmaceutical composition.
Inventor(s):	Jeffrey Owen Phillips
Assignee:	University of Missouri St Louis
Application Number:	US09/481,207
Patent Claim Types: see list of patent claims	Use; Composition; Formulation; Device; Dosage form;

Drugs Protected by US Patent 6,489,346

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 6,489,346

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Argentina	038157	⤷ Start Trial
Austria	340574	⤷ Start Trial
Australia	1907100	⤷ Start Trial
Australia	2002330863	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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