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Serving leading biopharmaceutical companies globally:

Citi
Covington
Federal Trade Commission
Johnson and Johnson
Fuji
Chubb
Julphar
UBS
AstraZeneca
Novartis

Generated: January 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,489,346

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Summary for Patent: 6,489,346
Title: Substituted benzimidazole dosage forms and method of using same
Abstract:There is provided a solid pharmaceutical composition in a dosage form that is not enteric-coated, having active ingredients including a non-enteric coated proton pump inhibitor and at least one buffering agent. The proton pump inhibitor is omeprazole, lansoprazole, rabeprazole, esomeprazole, pantoprazole, pariprazole, and leminoprazole, or an enantiomer, isomer, derivative, free base, or salt thereof, in an amount of approximately 5 mg to approximately 300 mg; and the buffering agent is in an amount of approximately 0.1 mEq to approximately 2.5 mEq per mg of proton pump inhibitor. The dosage form includes a suspension tablet, a chewable tablet, an effervescent powder, or an effervescent tablet. Also provided is a method for treating an acid-related gastrointestinal disorder in a subject in need thereof by administering to the subject a solid pharmaceutical composition.
Inventor(s): Phillips; Jeffrey Owen (Ashland, MO)
Assignee: The Curators of the University of Missouri (Columbia, MO)
Application Number:09/481,207
Patent Claim Types:
see list of patent claims
Composition; Dosage form; Use; Formulation; Device;

Drugs Protected by US Patent 6,489,346

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Bayer Healthcare Llc ZEGERID OTC omeprazole; sodium bicarbonate CAPSULE;ORAL 022281-001 Dec 1, 2009 OTC Yes Yes ➤ Subscribe ➤ Subscribe Y Y TREATING FREQUENT HEARTBURN ➤ Subscribe
Santarus Inc ZEGERID omeprazole; sodium bicarbonate FOR SUSPENSION;ORAL 021636-001 Jun 15, 2004 AB RX Yes No ➤ Subscribe ➤ Subscribe Y Y SHORT-TERM TREATMENT OF ACTIVE DUODENAL ULCER; TREATMENT OF HEARTBURN AND OTHER SYMPTOMS ASSOCIATED WITH GERD; SHORT-TERM TREATMENT OF EROSIVE ESOPHAGITIS; MAINTENANCE OF HEALING OF EROSIVE ESOPHAGITIS ➤ Subscribe
Santarus Inc ZEGERID omeprazole; sodium bicarbonate FOR SUSPENSION;ORAL 021636-002 Dec 21, 2004 AB RX Yes Yes ➤ Subscribe ➤ Subscribe Y Y SHORT TERM TREATMENT OF ACTIVE BENIGN GASTRIC ULCER ➤ Subscribe
Santarus Inc ZEGERID omeprazole; sodium bicarbonate FOR SUSPENSION;ORAL 021636-002 Dec 21, 2004 AB RX Yes Yes ➤ Subscribe ➤ Subscribe Y Y REDUCTION OF RISK OF UPPER GASTROINTESTINAL BLEEDING IN CRITICALLY ILL PATIENTS ➤ Subscribe
Santarus ZEGERID magnesium hydroxide; omeprazole; sodium bicarbonate TABLET, CHEWABLE;ORAL 021850-001 Mar 24, 2006 DISCN No No ➤ Subscribe ➤ Subscribe Y Y SHORT-TERM TREATMENT OF ACTIVE DUODENAL ULCER; TREATMENT OF HEARTBURN AND OTHER SYMPTOMS ASSOCIATED WITH GERD; SHORT-TERM TREATMENT OF EROSIVE ESOPHAGITIS; MAINTENANCE OF HEALING OF EROSIVE ESOPHAGITIS ➤ Subscribe
Santarus ZEGERID magnesium hydroxide; omeprazole; sodium bicarbonate TABLET, CHEWABLE;ORAL 021850-002 Mar 24, 2006 DISCN No No ➤ Subscribe ➤ Subscribe Y Y SHORT TERM TREATMENT OF ACTIVE BENIGN GASTRIC ULCER ➤ Subscribe
Santarus MAGNESIUM HYDROXIDE AND OMEPRAZOLE AND SODIUM BICARBONATE magnesium hydroxide; omeprazole; sodium bicarbonate TABLET;ORAL 022456-001 Dec 4, 2009 DISCN No No ➤ Subscribe ➤ Subscribe Y SHORT-TERM TREATMENT OF ACTIVE DUODENAL ULCER; TREATMENT OF HEARTBURN AND OTHER SYMPTOMS ASSOCIATED WITH GERD; SHORT-TERM TREATMENT OF EROSIVE ESOPHAGITIS; MAINTENANCE OF HEALING OF EROSIVE ESOPHAGITIS ➤ Subscribe
Santarus MAGNESIUM HYDROXIDE AND OMEPRAZOLE AND SODIUM BICARBONATE magnesium hydroxide; omeprazole; sodium bicarbonate TABLET;ORAL 022456-001 Dec 4, 2009 DISCN No No ➤ Subscribe ➤ Subscribe Y SHORT-TERM TREATMENT (4-8 WEEKS) OF ACTIVE BENIGN GASTRIC ULCER ➤ Subscribe
Santarus MAGNESIUM HYDROXIDE AND OMEPRAZOLE AND SODIUM BICARBONATE magnesium hydroxide; omeprazole; sodium bicarbonate TABLET;ORAL 022456-002 Dec 4, 2009 DISCN No No ➤ Subscribe ➤ Subscribe Y SHORT-TERM TREATMENT OF ACTIVE DUODENAL ULCER; TREATMENT OF HEARTBURN AND OTHER SYMPTOMS ASSOCIATED WITH GERD; SHORT-TERM TREATMENT OF EROSIVE ESOPHAGITIS; MAINTENANCE OF HEALING OF EROSIVE ESOPHAGITIS ➤ Subscribe
Santarus MAGNESIUM HYDROXIDE AND OMEPRAZOLE AND SODIUM BICARBONATE magnesium hydroxide; omeprazole; sodium bicarbonate TABLET;ORAL 022456-002 Dec 4, 2009 DISCN No No ➤ Subscribe ➤ Subscribe Y SHORT-TERM TREATMENT (4-8 WEEKS) OF ACTIVE BENIGN GASTRIC ULCER ➤ Subscribe
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 6,489,346

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
5,840,737 Omeprazole solution and method for using same ➤ Subscribe
7,399,772 Substituted benzimidazole dosage forms and method of using same ➤ Subscribe
RE45198 Omeprazole solution and method for using same ➤ Subscribe
6,645,988 Substituted benzimidazole dosage forms and method of using same ➤ Subscribe
6,699,885 Substituted benzimidazole dosage forms and methods of using same ➤ Subscribe
6,780,882 Substituted benzimidazole dosage forms and method of using same ➤ Subscribe
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 6,489,346

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 038157 ➤ Subscribe
Austria 340574 ➤ Subscribe
Australia 1907100 ➤ Subscribe
Australia 2002330863 ➤ Subscribe
Australia 2003214858 ➤ Subscribe
Australia 2005229686 ➤ Subscribe
Australia 3276701 ➤ Subscribe
Australia 782488 ➤ Subscribe
Brazil 0107565 ➤ Subscribe
Brazil 0210971 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

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Serving leading biopharmaceutical companies globally:

Citi
Chubb
Cantor Fitzgerald
Novartis
Daiichi Sankyo
Dow
Harvard Business School
Colorcon
UBS

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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