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Details for Patent: 6,455,518

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Patent 6,455,518 protects ZORTRESS and is included in one NDA. There has been one Paragraph IV challenge on Zortress.

Protection for ZORTRESS has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

Summary for Patent: 6,455,518

Title: Pharmaceutical compositions for the treatment of transplant rejection, autoimmune or inflammatory conditions comprising cyclosporin a and 40-O-(2-hydroxyethyl)-rapamycin
Abstract:A synergistic combination of an IL-2 transcription inhibitor (e.g., cyclosporin A or FK506) and 40-O-(2-hydroxyethyl)-rapamycin is provided, which is useful in the treatment and prevention of transplant rejection and also certain autoimmune and inflammatory diseases, together with novel pharmaceutical compositions comprising an IL-2 transcription inhibitor in combination with a rapamycin, e.g., 40-O-(2-hydroxyethyl)-rapamycin.
Inventor(s): Zenke; Gerhard (Rheinfelden, DE), Schuurman; Hendrik (Basel, CH), Haeberlin; Barbara (Riehen, CH), Meinzer; Armin (Buggingen, DE)
Assignee: Novartis AG (Basel, CH)
Application Number:09/758,301
Patent Claim Types:
see list of patent claims
Compound; Composition; Formulation; Use; Dosage form; Device;
Patent Metrics:
Source: PatentQuant.com
Field: Pharmaceuticals
Back Citations: 12th percentile
Forward Citations: 2nd percentile

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
TABLET;ORAL021560-001Apr 20, 2010RXNo6,455,518*PEDJan 29, 2018Y
TABLET;ORAL021560-002Apr 20, 2010RXNo6,455,518*PEDJan 29, 2018Y
TABLET;ORAL021560-003Apr 20, 2010RXYes6,455,518*PEDJan 29, 2018Y
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Foreign Priority and PCT Information for Patent: 6,455,518

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9615942Jul 30, 1996
United Kingdom9705684Mar 19, 1997

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