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Serving leading biopharmaceutical companies globally:

Merck
US Army
Daiichi Sankyo
Citi
Julphar
Boehringer Ingelheim
Cipla
Novartis
Farmers Insurance
AstraZeneca

Generated: February 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,455,518

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Which drugs does patent 6,455,518 protect, and when does it expire?

Patent 6,455,518 protects ZORTRESS and is included in one NDA.

Protection for ZORTRESS has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.
Summary for Patent: 6,455,518
Title: Pharmaceutical compositions for the treatment of transplant rejection, autoimmune or inflammatory conditions comprising cyclosporin a and 40-O-(2-hydroxyethyl)-rapamycin
Abstract:A synergistic combination of an IL-2 transcription inhibitor (e.g., cyclosporin A or FK506) and 40-O-(2-hydroxyethyl)-rapamycin is provided, which is useful in the treatment and prevention of transplant rejection and also certain autoimmune and inflammatory diseases, together with novel pharmaceutical compositions comprising an IL-2 transcription inhibitor in combination with a rapamycin, e.g., 40-O-(2-hydroxyethyl)-rapamycin.
Inventor(s): Zenke; Gerhard (Rheinfelden, DE), Schuurman; Hendrik (Basel, CH), Haeberlin; Barbara (Riehen, CH), Meinzer; Armin (Buggingen, DE)
Assignee: Novartis AG (Basel, CH)
Application Number:09/758,301
Patent Claim Types:
see list of patent claims
Compound; Composition; Formulation; Use; Dosage form; Device;

Drugs Protected by US Patent 6,455,518

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Novartis ZORTRESS everolimus TABLET;ORAL 021560-001 Apr 20, 2010 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Novartis ZORTRESS everolimus TABLET;ORAL 021560-002 Apr 20, 2010 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Novartis ZORTRESS everolimus TABLET;ORAL 021560-003 Apr 20, 2010 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 6,455,518

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9615942Jul 30, 1996
United Kingdom9705684Mar 19, 1997

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Teva
Harvard Business School
Medtronic
UBS
Baxter
Colorcon
McKinsey
Boehringer Ingelheim
McKesson

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