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Serving leading biopharmaceutical companies globally:

Federal Trade Commission
Farmers Insurance
McKesson
Harvard Business School
Chubb
Cantor Fitzgerald
Dow
US Army
Fuji
Argus Health

Generated: January 17, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,419,953

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Which drugs does patent 6,419,953 protect, and when does it expire?

Patent 6,419,953 protects DEPAKOTE ER and is included in one NDA.

Protection for DEPAKOTE ER has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

This patent has thirty-seven patent family members in twenty-seven countries.
Summary for Patent: 6,419,953
Title: Controlled release formulation of divalproex sodium
Abstract:The present invention pertains to a hydrophilic matrix tablet suitable for the once-a-day administration of valproate compounds such as divalproex sodium. The tablet comprises from about 50 weight percent to about 55 weight percent of an active ingredient selected from the group consisting of valproic acid, a pharmaceutically acceptable salt or ester of valproic acid, divalproex sodium, and valpromide; from about 20 weight percent to about 40 weight percent hydroxypropyl methylcellulose; from about 5 weight percent to about 15 weight percent lactose, from about 4 weight percent to about 6 weight percent microcrystalline cellulose, and from about 1 weight percent to about 5 weight percent of silicon dioxide; all weight percentages based upon the total weight of the tablet dosage form. Other aspects of the invention relate to the use of this formulation in the treatment of epilepsy and to methods for manufacturing this dosage form.
Inventor(s): Qiu; Yihong (Gurnee, IL), Poska; Paul Richard (Mundelein, IL), Cheskin; Howard S. (Glencoe, IL), Bollinger; J. Daniel (Libertyville, IL), Engh; Robert K. (Kenosha, WI)
Assignee: Abbott Laboratories (Abbott Park, IL)
Application Number:09/216,650
Patent Claim Types:
see list of patent claims
Compound; Dosage form; Formulation; Composition; Use;

Drugs Protected by US Patent 6,419,953

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Abbvie DEPAKOTE ER divalproex sodium TABLET, EXTENDED RELEASE;ORAL 021168-001 Aug 4, 2000 AB RX Yes Yes ➤ Subscribe ➤ Subscribe Y ➤ Subscribe
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 6,419,953

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,720,004 Controlled release formulation of divalproex sodium ➤ Subscribe
6,511,678 Controlled release formulation of divalproex sodium ➤ Subscribe
6,528,090 Controlled release formulation of divalproex sodium ➤ Subscribe
6,713,086 Controlled release formulation of divalproex sodium ➤ Subscribe
6,528,091 Controlled release formulation of divalproex sodium ➤ Subscribe
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 6,419,953

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Taiwan 585788 ➤ Subscribe
Turkey 200402549 ➤ Subscribe
Slovakia 8252001 ➤ Subscribe
Slovenia 20624 ➤ Subscribe
Portugal 1216704 ➤ Subscribe
Portugal 1140034 ➤ Subscribe
Poland 356899 ➤ Subscribe
Norway 20012986 ➤ Subscribe
South Korea 20010101295 ➤ Subscribe
Japan 2003513882 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

McKinsey
Harvard Business School
Express Scripts
Federal Trade Commission
Daiichi Sankyo
Baxter
Colorcon
Farmers Insurance
AstraZeneca

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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