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Last Updated: January 21, 2020

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Details for Patent: 6,417,191

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Summary for Patent: 6,417,191
Title: Synergistic combinations of zidovudine, 1592U89 and 3TC
Abstract:The present invention relates to therapeutic combinations of (1S,4R)-cis-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene- 1-methanol (1592U89), 3'-azido-3'-deoxythymidine (zidovudine) and (2R,cis)-4-amino-]-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin- 2-one (3TC) (or, alternatively to 3TC, (2R,cis)-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyr imidin-2-one (FTC)) which have anti-HIV activity. The present invention is also concerned with pharmaceutical compositions containing said combinations and their use in the treatment of HIV infections including infections with HIV mutants bearing resistance to nucleoside and/or non-nucleoside inhibitors.
Inventor(s): Barry; David Walter (Chapel Hill, NC), St. Clair; Martha Heider (Rougemont, NC)
Assignee: GlaxoSmithKline (Research Triangle Park, NC)
Application Number:08/930,225
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,417,191
Patent Claim Types:
see list of patent claims
Use; Dosage form; Formulation; Composition;

Drugs Protected by US Patent 6,417,191

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 6,417,191

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9506489Mar 30, 1995
United Kingdom9506490Mar 30, 1995
PCT Information
PCT FiledMarch 28, 1996PCT Application Number:PCT/EP96/01352
PCT Publication Date:October 03, 1996PCT Publication Number: WO96/30025

International Family Members for US Patent 6,417,191

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
African Regional IP Organization (ARIPO) 652   Start Trial
African Regional IP Organization (ARIPO) 9701089   Start Trial
Austria 220551   Start Trial
Australia 5497296   Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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