Generated: December 12, 2017
DrugPatentWatch Database Preview
Details for Patent: 6,410,511
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Summary for Patent: 6,410,511
|Title:|| Formulations for amylin agonist peptides|
|Abstract:||The present invention is concerned with a pharmaceutical formulation in a container, for example, a vial, prefilled cartridge, prefilled syringe or disposable pen, comprising approximately 0.01 to about 0.5% (w/v) amylin agonist, preferably pramlintide, in an aqueous system along with approximately 0.02 to about 0.5% (w/v) of an acetate, phosphate, citrate, or glutamate buffer to a pH of the final composition of approximately 3.0 to about 6.0 as well as approximately 1.0 to 10% (w/v) of a carbohydrate or polyhydric alcohol tonicifier; and, optionally, approximately 0.005 to 1.0% (w/v) of a preservative selected from the group consisting of m-cresol, benzyl alcohol, parabens and phenol. These formulations maintain stability upon storage under refrigerated or room temperature conditions. Such formulations can be further combined with insulin in the same syringe for administration to a patient.|
|Inventor(s):|| L'Italien; James (Del Mar, CA), Musunuri; Shankar (Exton, PA), Ruby; Kale (San Diego, CA) |
|Assignee:|| Amylin Pharmaceuticals, Inc. (San Diego, CA) |
Patent Claim Types:|
see list of patent claims
|Formulation; Compound; Composition; Use; Dosage form; |
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International Patent Family for Patent: 6,410,511
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