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Serving leading biopharmaceutical companies globally:

Cipla
Queensland Health
Fish and Richardson
Colorcon
McKinsey
Baxter
Chubb
US Army
Teva
Dow

Generated: January 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,395,767

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Summary for Patent: 6,395,767
Title: Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
Abstract:Dipeptidyl peptidase IV (DP 4) inhibiting compounds are provided having the formula ##STR1## where x is 0 or 1 and y is 0 or 1 (provided that x=1 when y=0 and x=0 when y=1); n is 0 or 1; X is H or CN; and wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, and other diseases as set out herein, employing such DP 4 inhibitor *or a combination of such DP 4 inhibitor and one or more of another antidiabetic agent such as metformin, glyburide, troglitazone, pioglitazone, rosiglitazone and/or insulin and/or one or more of a hypolipidemic agent and/or anti-obesity agent and/or other therapeutic agent.
Inventor(s): Robl; Jeffrey A. (Newtown, PA), Sulsky; Richard B. (West Trenton, NJ), Augeri; David J. (Princeton, NJ), Magnin; David R. (Hamilton, NJ), Hamann; Lawrence G. (Cherry Hill, NJ), Betebenner; David A. (Lawrenceville, NJ)
Assignee: Bristol-Myers Squibb Company (Princeton, NJ)
Application Number:09/788,173
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;

Drugs Protected by US Patent 6,395,767

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 6,395,767

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Czech Republic 304355 ➤ Subscribe
Germany 60134122 ➤ Subscribe
Germany 122010000008 ➤ Subscribe
Germany 122012000023 ➤ Subscribe
Denmark 1261586 ➤ Subscribe
Egypt 25854 ➤ Subscribe
European Patent Office 1261586 ➤ Subscribe C300436 Netherlands ➤ Subscribe
European Patent Office 1261586 ➤ Subscribe CA 2010 00007 Denmark ➤ Subscribe
European Patent Office 1261586 ➤ Subscribe 91650 Luxembourg ➤ Subscribe
European Patent Office 1261586 ➤ Subscribe SPC005/2010 Ireland ➤ Subscribe
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Serving leading biopharmaceutical companies globally:

Daiichi Sankyo
Chinese Patent Office
Julphar
QuintilesIMS
Moodys
Accenture
McKinsey
Teva
Harvard Business School

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