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Serving leading biopharmaceutical companies globally:

Cerilliant
Baxter
Julphar
Novartis
Argus Health
Citi
US Department of Justice
Chubb
Federal Trade Commission
McKesson

Generated: January 17, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,395,716

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Which drugs does patent 6,395,716 protect, and when does it expire?

Patent 6,395,716 protects TYZEKA and is included in two NDAs.

This patent has forty-four patent family members in twenty countries.
Summary for Patent: 6,395,716
Title: .beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B
Abstract:This invention is directed to a method for treating a host infected with hepatitis B comprising administering an effective amount of an anti-HBV biologically active 2'-deoxy-.beta.-L-erythro-pentofuranonucleoside or a pharmaceutically acceptable salt or prodrug thereof, wherein the 2'-deoxy-.beta.-L-erythro-pentofuranonucleoside has the formula: ##STR1## wherein R is selected from the group consisting of H, straight chained, branched or cyclic alkyl, CO-alkyl, CO-aryl, CO-alkoxyalkyl, CO-aryloxyalkyl, CO-substituted aryl, alkylsulfonyl, arylsulfonyl, aralkylsulfonyl, amino acid residue, mono, di, or triphosphate, or a phosphate derivative; and BASE is a purine or pyrimidine base which may be optionally substituted. The 2'-deoxy-.beta.-L-erythro-pentofuranonucleoside or a pharmaceutically acceptable salt or prodrug thereof may be administered either alone or in combination with another 2'-deoxy-.beta.-L-erythro-pentofuranonucleoside or in combination with another anti-hepatitis B agent.
Inventor(s): Gosselin; Gilles (Montpellier, FR), Imbach; Jean-Louis (Montpellier, FR), Bryant; Martin L. (Carlisle, MA)
Assignee: Novirio Pharmaceuticals Limited (Grand Cayman, KY) Centre National da la Recherche Scientifique (Paris, FR)
Application Number:09/371,747
Patent Claim Types:
see list of patent claims
Use; Compound; Composition; Delivery; Dosage form;

Drugs Protected by US Patent 6,395,716

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Novartis TYZEKA telbivudine SOLUTION;ORAL 022154-001 Apr 28, 2009 DISCN No No ➤ Subscribe ➤ Subscribe TREATMENT OF CHRONIC HEPATITIS B IN ADULT PATIENTS ➤ Subscribe
Novartis TYZEKA telbivudine TABLET;ORAL 022011-001 Oct 25, 2006 RX Yes Yes ➤ Subscribe ➤ Subscribe TREATMENT OF CHRONIC HEPATITIS B IN ADULT PATIENTS WITH EVIDENCE OF VIRAL REPLICATION AND EITHER EVIDENCE OF PERSISTANT ELEVATIONS IN SERUM AMINOTRANSFERASES (ALT OR AST) OR HISTOLOGICALLY ACTIVE DISEASE ➤ Subscribe
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 6,395,716

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,946,450 .beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B ➤ Subscribe
2,011,195,922 ➤ Subscribe
9,290,533 .beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B ➤ Subscribe
6,444,652 .beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B ➤ Subscribe
7,304,043 .beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B ➤ Subscribe
6,569,837 .beta.-L-2'-deoxy pyrimidine nucleosides for the treatment of hepatitis B ➤ Subscribe
6,566,344 .beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B ➤ Subscribe
7,795,238 .beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B ➤ Subscribe
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 6,395,716

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Singapore 132498 ➤ Subscribe
Russian Federation 2424016 ➤ Subscribe
Russian Federation 2006147216 ➤ Subscribe
Russian Federation 2300381 ➤ Subscribe
Portugal 2415776 ➤ Subscribe
Portugal 1431304 ➤ Subscribe
Netherlands 300286 ➤ Subscribe
Mexico PA01001507 ➤ Subscribe
Luxembourg 91348 ➤ Subscribe
South Korea 100702230 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

Cerilliant
Farmers Insurance
QuintilesIMS
Dow
UBS
Moodys
US Army
Cantor Fitzgerald
Express Scripts

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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