Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving hundreds of leading biopharmaceutical companies globally:

Cerilliant
McKesson
UBS
Moodys
Mallinckrodt
Chubb
Fish and Richardson
Medtronic
Cipla

Generated: May 26, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,391,874

« Back to Dashboard

Summary for Patent: 6,391,874
Title: Fused heterocyclic compounds as protein tyrosine kinase inhibitors
Abstract:Substituted heteroaromatic compounds of formula (I) and in particular substituted quinolines and quinazolines, are protein tyrosine kinase inhibitors. The compounds are described as are methods for their preparation, pharmaceutical compositions including such compounds and their use in medicine, for example in the treatment of cancer and psoriasis, or a salt or solvate thereof; wherein X is N or CH; Y is a group W(CH.sub.2), (CH.sub.2)W, or W, in which W is O, S(O).sub.m wherein m is 0, 1 or 2, or NR.sup.a wherein R.sup.a is hydrogen or a C.sub.1-8 alkyl group; R.sup.1 represents a phenyl group or a 5- or 6-membered heterocyclic ring containing 1 to 4 heteroatoms selected from N, O or S(O).sub.m, wherein m is as defined above, with the provisos that the ring does not contain two adjacent O or S(O).sub.m atoms and that where the ring contains only N as heteroatom(s) the ring is C-linked to the quinazoline or quinoline ring, R.sup.1 being optionally substituted by one or more R.sup.3 ;groups; P=0 to 3; U, R.sup.2, R.sup.3 are as defined in the application. ##STR1##
Inventor(s): Cockerill; George Stuart (Herts, GB), Carter; Malcolm Clive (Herts, GB), Guntrip; Stephen Barry (Herts, GB), Smith; Kathryn Jane (Herts, GB)
Assignee: SmithKline Beecham Corporation (Philadelphia, PA)
Application Number:09/214,267
Patent Claim Types:
see list of patent claims
Compound; Composition; Formulation; Dosage form; Use;

Drugs Protected by US Patent 6,391,874

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

Foreign Priority and PCT Information for Patent: 6,391,874

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9614755Jul 13, 1996
United Kingdom9625458Dec 07, 1996
PCT Information
PCT FiledJuly 11, 1997PCT Application Number:PCT/EP97/03672
PCT Publication Date:January 22, 1998PCT Publication Number: WO98/02434

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Chinese Patent Office
Cantor Fitzgerald
Citi
Queensland Health
US Department of Justice
QuintilesIMS
Federal Trade Commission
Farmers Insurance

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.