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|Title:||Cyclic peptide antifungal agents and process for preparation thereof|
|Abstract:||Provided are compounds of the formula (1): ##STR1## wherein R' is hydrogen, methyl or NH.sub.2 C(O)CH.sub.2 --; R" and R'" are independently methyl or hydrogen; R and R.sup.y are independently hydroxy or hydrogen; R.sub.1 is hydroxy, hydrogen, or hydroxysulfonyloxy; R.sub.7 is hydroxy, hydrogen, hydroxysulfonyloxy or phosphonooxy; R.sub.2 is a acyl side chain. Also provided are formulations, methods of inhibiting fungal and parasitic activity, and a process for preparing dideoxy (R.dbd.H) forms of the compounds.|
|Inventor(s):||Burkhardt; Frederick J. (Indianapolis, IN), Debono; Manuel (Indianapolis, IN), Nissen; Jeffrey S. (Indianapolis, IN), Turner, Jr.; William W. (Bloomington, IN)|
|Assignee:||Eli Lilly and Company (Indianapolis, IN)|
Patent Claim Types:|
see list of patent claims
Back Citations: 29th percentile
Forward Citations: 10th percentile
|Patent Number||Expiration Date|
|6,384,013||May 07, 2014|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|China||1080926||<disabled in preview>|
|China||1036715||<disabled in preview>|
|Czech Republic||9300416||<disabled in preview>|
| This preview shows a limited data set|
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