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Serving leading biopharmaceutical companies globally:

Moodys
Fish and Richardson
Accenture
Novartis
Merck
McKesson
Cipla
Healthtrust
UBS
Johnson and Johnson

Generated: February 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,348,216

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Summary for Patent: 6,348,216
Title: Ibuprofen and narcotic analgesic compositions
Abstract:Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant. Also provided herein is a method of preparing a pharmaceutical tablet composition comprising: (a) Granulating ibuprofen, a narcotic analgesic, a first glidant, a first disintegrant, a binder, and starch to form granules wherein said granulating step comprises a wet granulation process; (b) blending the granules with extra-granular material comprised of a second glidant, a second disintegrant, a filler and starch to form a blend of granules and extra-granular material; and (c) compressing the blend into a tablet.
Inventor(s): Kushla; Gregory P. (Florham Park, NJ), Lai; Jin-Wang (Edison, NJ), Polli; Gerald P. (Valley Forge, PA)
Assignee: Knoll Pharmaceutical Company (Mt. Olive, NJ)
Application Number:08/872,216
Patent Claim Types:
see list of patent claims
Composition; Dosage form; Formulation; Process;

Drugs Protected by US Patent 6,348,216

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

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US Department of Justice
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Boehringer Ingelheim
Fuji
Cerilliant
Dow

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