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Serving hundreds of leading biopharmaceutical companies globally:

Teva
Chubb
Merck
Mallinckrodt
Colorcon
Cipla
Fuji
Julphar
Medtronic

Generated: May 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,287,539

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Summary for Patent: 6,287,539
Title: Methods of imaging using osmotically stabilized microbubble preparations
Abstract:A microbubble preparation formed of a plurality of microbubbles comprising a first gas and a second gas surrounded by a membrane such as a surfactant, wherein the first gas and the second gas are present in a molar ratio of from about 1:100 to about 1000:1, and wherein the first gas has a vapor pressure of at least about (760-x) mm Hg at 37.degree. C., where x is the vapor pressure of the second gas at 37.degree. C., and wherein the vapor pressure of each of the first and second gases is greater than about 75 mm Hg at 37.degree. C.; also disclosed are methods for preparing microbubble compositions, including compositions that rapidly shrink from a first average diameter to a second average diameter less than about 75% of the first average diameter and are stabilized at the second average diameter; methods and kits for preparing microbubbles; and methods for using such microbubbles as contrast agents.
Inventor(s): Schutt; Ernest G. (San Diego, CA), Anderson; Charles David (Lebanon, NJ), Evitts; David P. (La Jolla, CA)
Assignee: Alliance Pharmaceuticals Corp. (San Diego, CA)
Application Number:08/841,846
Patent Claim Types:
see list of patent claims
Use; Dosage form; Compound;

Drugs Protected by US Patent 6,287,539

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

Dow
McKesson
Julphar
Chinese Patent Office
Argus Health
Daiichi Sankyo
Queensland Health
Fish and Richardson
Teva

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