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Details for Patent: 6,248,741

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Summary for Patent: 6,248,741

Title: Method of using (2-imidazolin-2-ylamino) quinoxalines in treating ocular neural injury
Abstract:The present invention provides a method of providing neuroprotection to a mammal comprising administering to said mammal suffering from or at risk of suffering a noxious action on its nerve cells an effective amount of a compound of formula I to inhibit or prevent nerve cell injury or death ##STR1## wherein the 2-imidazolin-2-ylamino group is in either the 5- or 6-position of the quinoxaline nucleus; x, y and z are in any of the remaining 5-, 6-, 7- or 8-positions and are selected from hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl; and R is an optional substituent in either the 2- or 3-position of the quinoxaline nucleus and may be hydrogen, lower alkyl or lower alkoxy, or pharmaceutically acceptable salts thereof and mixtures thereof. Such noxious action may result from ischemia, e.g. spinal ischemia.
Inventor(s): Wheeler; Larry A. (Irvine, CA), Woldemussie; Elizabeth (Laguna Niguel, CA), Lai; Ronald K. (Irvine, CA)
Assignee: Allergan Sales, Inc. (Irvine, CA)
Application Number:09/655,579
Patent Claim Types:
see list of patent claims
Use; Delivery;
Patent Metrics:
Source: PatentQuant.com
Field: Not categorized
Back Citations: 8th percentile
Forward Citations: 2nd percentile

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Premature patent expiration for: 6,248,741

Expiration due to failure to pay maintenance fee

Patent Number Expiration Date
6,248,741 June 19, 2009

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