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Serving hundreds of leading biopharmaceutical companies globally:

Deloitte
Boehringer Ingelheim
Argus Health
Cerilliant
Express Scripts
UBS
Farmers Insurance
Julphar
Moodys

Generated: May 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,239,124

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Which drugs does patent 6,239,124 protect, and when does it expire?

Patent 6,239,124 protects ZORTRESS and is included in one NDA.

Protection for ZORTRESS has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

This patent has twenty-two patent family members in fifteen countries.
Summary for Patent: 6,239,124
Title: Pharmaceutical compositions for the treatment of transplant rejection or autoimmune or inflammatory conditions comprising cyclosporin A and 40-0-(2-hydroxyethyl)-rapamycin
Abstract:A synergistic combination of an IL-2 transcription inhibitor (e.g., cyclosporin A or FK506) and 40-O-(2-hydroxyethyl)-rapamycin is provided, which is useful in the treatment and prevention of transplant rejection and also certain autoimmune and inflammatory diseases, together with novel pharmaceutical compositions comprising an IL-2 transcription inhibitor in combination with a rapamycin, e.g., 40-O-(2-hydroxyethyl)-rapamycin.
Inventor(s): Zenke; Gerhard (Rheinfelden, DE), Schuurman; Hendrik (Basel, CH), Haeberlin; Barbara (Riehen, CH), Meinzer; Armin (Buggingen, DE)
Assignee: Novartis AG (Basel, CH)
Application Number:09/230,618
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,239,124
Patent Claim Types:
see list of patent claims
Composition; Formulation; Use; Dosage form; Device;

Drugs Protected by US Patent 6,239,124

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Novartis ZORTRESS everolimus TABLET;ORAL 021560-001 Apr 20, 2010 AB RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Novartis ZORTRESS everolimus TABLET;ORAL 021560-002 Apr 20, 2010 AB RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Novartis ZORTRESS everolimus TABLET;ORAL 021560-003 Apr 20, 2010 AB RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 6,239,124

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9615942Jul 30, 1996
United Kingdom9705684Mar 19, 1997
PCT Information
PCT FiledJuly 29, 1997PCT Application Number:PCT/EP97/04123
PCT Publication Date:February 05, 1998PCT Publication Number: WO98/04279

Non-Orange Book US Patents Family Members for Patent 6,239,124

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,455,518 Pharmaceutical compositions for the treatment of transplant rejection, autoimmune or inflammatory conditions comprising cyclosporin a and 40-O-(2-hydroxyethyl)-rapamycin ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

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International Family Members for US Patent 6,239,124

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 222502 ➤ Try a Free Trial
Austria 340586 ➤ Try a Free Trial
Australia 4012497 ➤ Try a Free Trial
Australia 730781 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Fuji
Citi
Argus Health
Covington
Medtronic
Harvard Business School
Colorcon
Chubb
Cantor Fitzgerald

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