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Serving leading biopharmaceutical companies globally:

Fish and Richardson
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Generated: November 23, 2017

DrugPatentWatch Database Preview

Details for Patent: 6,171,294

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Summary for Patent: 6,171,294

Title: Method and device for transdermal electrotransport delivery of fentanyl and sufentanil
Abstract:The invention provides an improved electrotransport drug delivery system for analgesic drugs, namely fentanyl and sufentanil. The fentanyl/sufentanil is provided as a water soluble salt (eg, fentanyl hydrochloride) dispersed in a hydrogel formulation for use in an electrotransport device (10). In accordance with one aspect of the invention, the concentration of fentanyl/sufentanil in the donor reservoir (26) solution is above a predetermined minimum concentration, whereby the transdermal electrotransport flux of fentanyl/sufentanil is maintained independent of the concentration of fentanyl/sufentanil in solution. In accordance with a second aspect of the present invention, the donor reservoir (26) of the electrotransport delivery device (10) is comprised of silver and the donor reservoir (26) contains a predetermined "excess" loading of fentanyl/sufentanil halide to prevent silver ion migration with attendant skin discoloration. In accordance with a third aspect of the present invention, a transdermal electrotransport delivered dose of fentanyl/sufentanil is provided which is sufficient to induce analgesia in (eg, adult) human patients suffering from moderate-to-severe pain associated with major surgical procedures.
Inventor(s): Southam; Mary (Portola Valley, CA), Bernstein; Keith J. (Somerville, NJ), Noorduin; Henk (Bergen op Zoom, NL)
Assignee: ALZA Corporation (Mountain View, CA)
Application Number:08/890,966
Patent Claim Types:
see list of patent claims
Use; Formulation; Delivery; Device;

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International Patent Family for Patent: 6,171,294

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
France2734729► Subscribe
Finland974418► Subscribe
Spain2218586► Subscribe
European Patent Office0836511► Subscribe91265Luxembourg► Subscribe
European Patent Office0836511► SubscribeCA 2006 00019Denmark► Subscribe
European Patent Office0836511► SubscribeSPC/GB06/022United Kingdom► Subscribe
European Patent Office0836511► Subscribe122006000022Germany► Subscribe
Denmark0836511► Subscribe
Germany69632131► Subscribe
Germany122006000022► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Chinese Patent Office
Harvard Business School
US Department of Justice
Cantor Fitzgerald

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