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Generated: August 18, 2017

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Title: Polymorphs of donepezil hydrochloride and process for production
Abstract:Donepezil hydrochloride, 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride, is provided here in the form of four polymorphs which are stable against heat and humidity in the pharmaceutical use. They can be industrially produced. They are specified by peaks in X-ray powder diffraction pattern and absorption peaks in infrared absorption spectra in potassium bromide.
Inventor(s): Imai; Akio (Ibaraki, JP), Watanabe; Hideaki (Ibaraki, JP), Kajima; Takashi (Ibaraki, JP), Ishihama; Yasushi (Ibaraki, JP), Ohtsuka; Akiyo (Ibaraki, JP), Tanaka; Tomohide (Ibaraki, JP)
Assignee: Eisai Co., Ltd. (Tokyo, JP)
Application Number:08/774,802
Patent Claim Types:
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Compound; Process; Use; Composition;

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Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan8-146293Jun 07, 1996

International Patent Family for Patent: ► Subscribe

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Hong Kong1080078► Subscribe
Hungary0002270► Subscribe
Hungary227539► Subscribe
Hungary0900417► Subscribe
JapanH1053576► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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