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Last Updated: March 29, 2024

Details for Patent: 6,110,503


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Summary for Patent: 6,110,503
Title: Preparation of biodegradable, biocompatible microparticles containing a biologically active agent
Abstract:A method for preparing biodegradable, biocompatible microparticles. A first phase is prepared that includes a biodegradable, biocompatible polymer, an active agent, and a solvent. An immiscible second phase is prepared. The first and second phases are combined to form an emulsion in which the first phase is discontinuous and the second phase is continuous. The two phases are immersed in a quench liquid that includes a quench medium and a quantity of the solvent. The quantity of the solvent is selected to control a rate of extraction of the solvent from the first phase. The first phase is isolated in the form of microparticles. Also disclosed is a microencapsulated active agent prepared by the method for preparing biodegradable, biocompatible microparticles.
Inventor(s): Rickey; Michael E. (Loveland, OH), Ramstack; J. Michael (Lebanon, OH), Lewis; Danny H. (Hartselle, AL)
Assignee: Alkermes Controlled Therapeutics Inc. (Cambridge, MA)
Application Number:09/263,098
Patent Claim Types:
see list of patent claims
Use; Process; Formulation;

Drugs Protected by US Patent 6,110,503

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
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