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Serving leading biopharmaceutical companies globally:

Farmers Insurance
Express Scripts
Queensland Health

Generated: December 15, 2017

DrugPatentWatch Database Preview

Details for Patent: 6,071,534

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Summary for Patent: 6,071,534

Title: Multivesicular liposomes with controlled release of active agents encapsulated in the presence of a hydrochloride
Abstract:Disclosed are multivesicular liposomes containing biologically active substances, and having defined size distribution, adjustable average size, adjustable internal chamber size and number, and a modulated release of the biologically active substance. The liposomes are made by a process comprising dissolving a lipid component in volatile organic solvents, adding an immiscible aqueous component containing at least one biologically active substance to be encapsulated, and adding to either or both the organic solvents and the lipid component, a hydrochloride effective to control the release rate of the biologically active substance from the multivesicular liposome. A water-in-oil emulsion is made from the two components, the emulsion is immersed into a second aqueous component, and then divided into small solvent spherules which contain even smaller aqueous chambers. The solvents arc finally removed to give an aqueous suspension of multivesicular liposomes encapsulating biologically active substances.
Inventor(s): Kim; Sinil (Solana Beach, CA), Howell; Stephen B. (Del Mar, CA)
Assignee: SkyePharma Inc. (San Diego, CA)
Application Number:09/019,337
Patent Claim Types:
see list of patent claims
Dosage form; Process; Device;

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International Patent Family for Patent: 6,071,534

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Germany3879987► Subscribe
Canada1323568► Subscribe
Denmark93988► Subscribe
Denmark172057► Subscribe
European Patent Office0280503► Subscribe
Finland95439► Subscribe
United Kingdom8704171► Subscribe
Spain2053722► Subscribe
Finland880841► Subscribe
Australia1205588► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Queensland Health
Johnson and Johnson
Argus Health
Federal Trade Commission
Farmers Insurance

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