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Serving hundreds of leading biopharmaceutical companies globally:

Chinese Patent Office
Mallinckrodt
Federal Trade Commission
Dow
Fish and Richardson
Boehringer Ingelheim
McKesson
Covington
Accenture

Generated: May 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,071,534

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Summary for Patent: 6,071,534
Title: Multivesicular liposomes with controlled release of active agents encapsulated in the presence of a hydrochloride
Abstract:Disclosed are multivesicular liposomes containing biologically active substances, and having defined size distribution, adjustable average size, adjustable internal chamber size and number, and a modulated release of the biologically active substance. The liposomes are made by a process comprising dissolving a lipid component in volatile organic solvents, adding an immiscible aqueous component containing at least one biologically active substance to be encapsulated, and adding to either or both the organic solvents and the lipid component, a hydrochloride effective to control the release rate of the biologically active substance from the multivesicular liposome. A water-in-oil emulsion is made from the two components, the emulsion is immersed into a second aqueous component, and then divided into small solvent spherules which contain even smaller aqueous chambers. The solvents arc finally removed to give an aqueous suspension of multivesicular liposomes encapsulating biologically active substances.
Inventor(s): Kim; Sinil (Solana Beach, CA), Howell; Stephen B. (Del Mar, CA)
Assignee: SkyePharma Inc. (San Diego, CA)
Application Number:09/019,337
Patent Claim Types:
see list of patent claims
Dosage form; Process; Device;

Drugs Protected by US Patent 6,071,534

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

AstraZeneca
Teva
Covington
Queensland Health
McKesson
Federal Trade Commission
Fish and Richardson
Moodys
Express Scripts

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