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Serving leading biopharmaceutical companies globally:

Fish and Richardson
Johnson and Johnson
Queensland Health

Generated: November 25, 2017

DrugPatentWatch Database Preview

Details for Patent: 6,046,183

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Summary for Patent: 6,046,183

Title: Method of synergistic treatment for benign prostatic hyperplasia
Abstract:Disclosed is an improved treatment for men with benign prostatic hyperplasia (BPH), involving combination therapy of a 5.alpha.-reductase inhibitor, e.g. a 17.beta.-substituted 4-azasteroid, a 17.beta.-substituted non-azasteroid, 17.beta.-acyl-3-carboxy-androst-3,5-diene, benzoylaminophenoxybutanoic acid derivative, fused benz(thio)amide or cinnamoylamide derivative, aromatic 1,2-diethers or thioethers, aromatic ortho acylaminophenoxy alkanoic acids, ortho thioalkylacylaminophenoxy alkanoic acids, pharmaceutically acceptable salts and esters thereof, and particularly finasteride, in combination with an .alpha..sub.1 -adrenergic receptor blocker, i.e., terazosin. The combination provides therapy at the molecular level for the underlying cause of the disease as well as providing symptomatic relief. Pharmaceutical compositions useful for treatment are also disclosed.
Inventor(s): Gormley; Glenn J. (Westfield, NJ), Stoner; Elizabeth (Westfield, NJ)
Assignee: Merck & Co., Inc. (Rahway, NJ)
Application Number:09/027,105
Patent Claim Types:
see list of patent claims
Use; Composition;

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International Patent Family for Patent: 6,046,183

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia1751492► Subscribe
Australia666846► Subscribe
Bulgaria61798► Subscribe
Bulgaria98113► Subscribe
Canada2104793► Subscribe
Czech Republic292712► Subscribe
Czech Republic9301933► Subscribe
European Patent Office0576603► Subscribe
Hungary9302624► Subscribe
HungaryT66273► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Harvard Business School
Queensland Health
Cantor Fitzgerald
Farmers Insurance

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