|Title:||Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia|
|Abstract:||This invention relates to the use of cyclooxygenase-2 inhibitors or derivatives thereof in preventing and treating neoplasia. In particular, the invention describes the method of preventing and treating epithelial cell neoplasia in a subject, said method comprising treating the subject with a therapeutically-effective amount of a compound of Formula I. ##STR1## wherein A, R.sup.2 and R.sup.3 are as described in the specification.|
|Inventor(s):||Seibert; Karen (St. Louis, MO), Masferrer; Jaime (Ballwin, MO), Gordon; Gary B (Highland Park, IL)|
|Assignee:||G.D. Searle & Co. (Skokie, IL)|
Patent Claim Types:|
see list of patent claims
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