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|Title:||Pharmaceutical formulations having improved disintegration and/or absorptivity|
|Abstract:||An oral solid dosage form, comprising a compressed tablet including an excipient comprising (a) microcrystalline cellulose; and (b) a compressibility augmenting agent which (I) physically restricts the proximity of the interface between adjacent cellulose surfaces (e.g., silicon dioxide); or (ii) inhibits interactions between adjacent cellulose surfaces (e.g., sodium lauryl sulfate); or (iii) accomplishes both (i) and (ii) above; together with an active agent, is disclosed which provides improved disintegration and/or absorptivity to the oral solid dosage form when orally administered to human patients. The excipient comprises agglomerated particles of said microcrystalline cellulose and said compressibility augmenting agent in intimate association with each other.|
|Inventor(s):||Staniforth; John N. (Bath, GB), Sherwood; Bob E. (Amenia, NY), Hunter; Edward A. (Glenham, NY)|
|Assignee:||Edward Mendell Co., Inc. (Patterson, NY)|
Patent Claim Types:|
see list of patent claims
|Dosage form; Composition;|
Field: Not categorized
Back Citations: 65th percentile
Forward Citations: 8th percentile
|Patent Number||Expiration Date|
|5,948,438||September 07, 2011|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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