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Serving leading biopharmaceutical companies globally:

Queensland Health
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Fish and Richardson
Daiichi Sankyo
Chinese Patent Office
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Generated: December 14, 2017

DrugPatentWatch Database Preview

Details for Patent: 5,925,760

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Summary for Patent: 5,925,760

Title: Method for preparing N.sup.2 -arylsulfonyl-L-argininamides
Abstract:A method for preparing N.sup.2 -(3-(a hydrogen atom or a lower alkyl)-8-quinolinesulfonyl)-N.sup.G -nitro-L-arginine which comprises the step of condensing N.sup.G -nitro-L-arginine and 3-(a hydrogen atom or a lower alkyl)-8-quinolinesulfonyl chloride. The method achieves an extremely efficient and high yield preparation of N.sup.2 -arylsulfonyl-L-arginineamides that are useful as active ingredients of medicaments. Also provided is a novel N.sup.2 -(3-(a hydrogen atom or a lower alkyl)-8-quinolinesulfonyl)-N.sup.G -nitro-L-arginine compound which can be used as synthetic intermediate for the manufacture of (2R,4R)-4-methyl-1-[N.sup.2 -(3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-arginyl]-2-piperidine -carboxylic acid.
Inventor(s): Kikumoto; Ryoji (Tokyo, JP)
Assignee: Mitsubishi Chemical Corporation (Tokyo, JP)
Application Number:08/904,555
Patent Claim Types:
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Process; Use;

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Foreign Priority and PCT Information for Patent: 5,925,760

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan8-208087Aug 07, 1996

International Patent Family for Patent: 5,925,760

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office0823430► Subscribe
Spain2166937► Subscribe
Germany69707603► Subscribe
Austria207482► Subscribe
JapanH10101649► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Express Scripts
Fish and Richardson
Federal Trade Commission
Farmers Insurance
Queensland Health

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