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Details for Patent: 5,912,238

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Patent 5,912,238 protects ELIDEL and is included in one NDA.

Protection for ELIDEL has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

Summary for Patent: 5,912,238

Title: Heteroatoms-containing tricyclic compounds
Abstract:The invention concerns the compounds of formula I ##STR1## wherein the substituents have various significances. They are prepared by several processes including epimerizing replacement, treatment with cyanogen bromide or thiophosgene, treatment with an acid having a non-nucleophilic anion, treatment with dimethylsulfoxide and acetic anhydride, acylation, treatment with an oxalyl derivative and ammonia, methylation, oxidation, deprotection and protection. They possess interesting pharmacological activity as antiinflammatory, immunosuppressant, antiproliferative and chemotherapeutic drug resistance reversing agents.
Inventor(s): Baumann; Karl (Vienna, AT), Emmer; Gerhard (Vienna, AT)
Assignee: Novartis AG (Basel, CH)
Application Number:08/276,276
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Valeant Bermuda
ELIDEL
pimecrolimus
CREAM;TOPICAL021302-001Dec 13, 2001RXYes5,912,238*PED► subscribeY
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Foreign Priority and PCT Information for Patent: 5,912,238

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Germany39 37 336Nov 09, 1989
Germany39 38 132Nov 16, 1989
Germany39 42 831Dec 23, 1989

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