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Last Updated: March 29, 2024

Details for Patent: 5,877,192


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Summary for Patent: 5,877,192
Title: Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole
Abstract:A method for treatment of gastric acid related diseases by inhibition of gastric acid secretion comprising administering to a mammal in need of treatment a therapeutically effective amount of the (-)-enantiomer of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benz imidazole or a pharmaceutically acceptable salt thereof, so as to effect decreased interindividual variation in plasma levels upon administration. The use of the (-)-enantiomer of omeprazole to receive increased average plasma levels (AUC) upon administration of the same doses of the (-)-enantiomer of omeprazole compared to those of racemic omeprazole is also claimed, as well as an improved antisecretory effect and a better clinical effect.
Inventor(s): Lindberg; Per (Molndal, SE), Weidolf; Lars (Vastra Frolunda, SE)
Assignee: Astra Aktiebolag (Sodertalje, SE)
Application Number:08/833,962
Patent Claim Types:
see list of patent claims
Use; Dosage form; Delivery; Composition;

Drugs Protected by US Patent 5,877,192

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 5,877,192

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Sweden9301830May 28, 1993
Sweden9601383Apr 11, 1996

International Family Members for US Patent 5,877,192

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 197452 ⤷  Try a Trial
Australia 676337 ⤷  Try a Trial
Australia 6902494 ⤷  Try a Trial
Canada 2139653 ⤷  Try a Trial
Canada 2337581 ⤷  Try a Trial
China 1055469 ⤷  Try a Trial
China 1107503 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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