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|Title:||Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole|
|Abstract:||A method for treatment of gastric acid related diseases by inhibition of gastric acid secretion comprising administering to a mammal in need of treatment a therapeutically effective amount of the (-)-enantiomer of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benz imidazole or a pharmaceutically acceptable salt thereof, so as to effect decreased interindividual variation in plasma levels upon administration. The use of the (-)-enantiomer of omeprazole to receive increased average plasma levels (AUC) upon administration of the same doses of the (-)-enantiomer of omeprazole compared to those of racemic omeprazole is also claimed, as well as an improved antisecretory effect and a better clinical effect.|
|Inventor(s):||Lindberg; Per (Molndal, SE), Weidolf; Lars (Vastra Frolunda, SE)|
|Assignee:||Astra Aktiebolag (Sodertalje, SE)|
Patent Claim Types:|
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|Use; Dosage form; Delivery; Composition;|
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