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Serving hundreds of leading biopharmaceutical companies globally:

US Army
Fish and Richardson
Cantor Fitzgerald
Queensland Health
Mallinckrodt
US Department of Justice
Daiichi Sankyo
Cerilliant
AstraZeneca

Generated: April 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,849,704

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Summary for Patent: 5,849,704
Title: Pharmaceutical formulation
Abstract:A pharmaceutical preparation comprising a growth hormone and histidine or a derivative of histidine as additive or buffering substance shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved preparation at ambient temperature. Crystallization of growth hormone in the presence of histidine or a derivative thereof gives rise to a higher yield of crystals having a higher purity than known methods.
Inventor(s): S.o slashed.rensen; Hans Holmegaard (Virum, DK), Skriver; Lars (Ved.ae butted.k, DK), Hoelgaard; Annie Rassing (Holte, DK)
Assignee: Novo Nordisk A/S (Bagsvaerd, DK)
Application Number:08/458,386
Patent Claim Types:
see list of patent claims
Composition; Compound; Formulation; Use;

Drugs Protected by US Patent 5,849,704

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 5,849,704

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Denmark2046/91Dec 20, 1991
Denmark1364/92Nov 10, 1992

International Patents Family Members for US Patent 5,849,704

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1197222 ➤ Try a Free Trial
European Patent Office 0618807 ➤ Try a Free Trial SPC008/2003 Ireland ➤ Try a Free Trial
Germany 69233704 ➤ Try a Free Trial
Denmark 136492 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Teva
Cantor Fitzgerald
Johnson and Johnson
Express Scripts
McKinsey
Colorcon
US Department of Justice
Baxter
Federal Trade Commission

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