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Serving leading biopharmaceutical companies globally:

Daiichi Sankyo
Harvard Business School
Johnson and Johnson
Moodys
Dow
Baxter
Cipla
McKinsey
Cantor Fitzgerald
Cerilliant

Generated: February 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,807,825

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Summary for Patent: 5,807,825
Title: Platelet aggregation inhibitors
Abstract:An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolated and purified PAI from several of these active snake venoms is described and characterized. In addition, PAIs lacking the Arg-Gly-Asp (RGD) adhesion sequence but containing K*-(G/Sar)-D wherein K* is a modified lysyl residue of the formula wherein each R.sup.1 is independently H, alkyl(1-6C) or at most one R.sup.1 is R.sup.2 --C.dbd.NR.sup.3 wherein R.sup.2 is H, alkyl(1-6C), phenyl or benzyl, or is NR.sup.4.sub.2 in which each R.sup.4 is independently H or alkyl(1-6C) and R is H, alkyl(1-6C), phenyl or benzyl, or R.sup.2 --C.dbd.NR.sup.3 is a radical selected from the group consisting of: ##STR1## where m is an integer of 2-3, and each R.sup.5 is independently H or alkyl(1-6C); and wherein one or two (CH.sub.2) may be replaced by O or S provided said O or S is not adjacent to another heteroatom are prepared and shown to specifically inhibit the binding of fibrinogen or von Willebrand Factor to GP IIb-IIIa.
Inventor(s): Scarborough; Robert M. (Belmont, CA), Wolf; David Lawrence (Palo Alto, CA), Charo; Israel F. (Lafayette, CA)
Assignee: COR Therapeutics, Inc. (South San Francisco, CA)
Application Number:08/482,278
Patent Claim Types:
see list of patent claims
Use; Device;

Drugs Protected by US Patent 5,807,825

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Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 5,807,825

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
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Australia 6036990 ➤ Sign Up
Australia 636159 ➤ Sign Up
Canada 2059124 ➤ Sign Up
Canada 2388770 ➤ Sign Up
Germany 19975072 ➤ Sign Up
Germany 69029579 ➤ Sign Up
Denmark 0477295 ➤ Sign Up
European Patent Office 0477295 ➤ Sign Up SPC/GB99/046 United Kingdom ➤ Sign Up
European Patent Office 0477295 ➤ Sign Up C990043 Netherlands ➤ Sign Up
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Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
US Department of Justice
Colorcon
Citi
Accenture
Teva
Medtronic
AstraZeneca
Daiichi Sankyo

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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