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Serving hundreds of leading biopharmaceutical companies globally:

Accenture
Medtronic
Chubb
Cantor Fitzgerald
US Army
Argus Health
Julphar
Covington
McKinsey

Generated: June 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,807,572

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Summary for Patent: 5,807,572
Title: Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
Abstract:Disclosed are multivesicular liposomes containing biologically active substances, the multivesicular liposomes having defined size distribution, adjustable average size, adjustable internal chamber size and number, and a modulated rate of the biologically active substance in contrast to the previous art. The process comprises dissolving a lipid component in volatile organic solvents, adding an immiscible aqueous component containing at least one biologically active substance to be encapsulated, and adding to either or both the organic solvents and the lipid component, a hydrochloride effective to control the release rate of the biologically active substance from the multivesicular liposome, making a water-in-oil emulsion from the two components, immersing the emulsion into a second aqueous component, dividing the emulsion into small solvent spherules which contain even smaller aqueous chambers, and then removing the solvents to give an aqueous suspension of multivesicular liposomes encapsulating biologically active substances.
Inventor(s): Kim; Sinil (Solana Beach, CA), Howell; Stephen B. (Del Mar, CA)
Assignee: DepoTech Corporation (La Jolla, CA)
Application Number:08/473,019
Patent Claim Types:
see list of patent claims
Dosage form; Process; Device;

Drugs Protected by US Patent 5,807,572

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Family Members for US Patent 5,807,572

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 87823 ➤ Try a Free Trial
Australia 1205588 ➤ Try a Free Trial
Australia 602190 ➤ Try a Free Trial
Canada 1323568 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Chubb
Accenture
Express Scripts
Julphar
Baxter
US Department of Justice
Healthtrust
Argus Health
Cipla

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