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Serving leading biopharmaceutical companies globally:

Novartis
Healthtrust
US Army
Fuji
US Department of Justice
Boehringer Ingelheim
Julphar
Daiichi Sankyo
Baxter
Cerilliant

Generated: January 18, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,807,572

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Summary for Patent: 5,807,572
Title: Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
Abstract:Disclosed are multivesicular liposomes containing biologically active substances, the multivesicular liposomes having defined size distribution, adjustable average size, adjustable internal chamber size and number, and a modulated rate of the biologically active substance in contrast to the previous art. The process comprises dissolving a lipid component in volatile organic solvents, adding an immiscible aqueous component containing at least one biologically active substance to be encapsulated, and adding to either or both the organic solvents and the lipid component, a hydrochloride effective to control the release rate of the biologically active substance from the multivesicular liposome, making a water-in-oil emulsion from the two components, immersing the emulsion into a second aqueous component, dividing the emulsion into small solvent spherules which contain even smaller aqueous chambers, and then removing the solvents to give an aqueous suspension of multivesicular liposomes encapsulating biologically active substances.
Inventor(s): Kim; Sinil (Solana Beach, CA), Howell; Stephen B. (Del Mar, CA)
Assignee: DepoTech Corporation (La Jolla, CA)
Application Number:08/473,019
Patent Claim Types:
see list of patent claims
Dosage form; Process; Device;

Drugs Protected by US Patent 5,807,572

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 5,807,572

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 87823 ➤ Subscribe
Australia 1205588 ➤ Subscribe
Australia 602190 ➤ Subscribe
Canada 1323568 ➤ Subscribe
Germany 3879987 ➤ Subscribe
Denmark 172057 ➤ Subscribe
Denmark 93988 ➤ Subscribe
European Patent Office 0280503 ➤ Subscribe
Spain 2053722 ➤ Subscribe
Finland 880841 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

Chinese Patent Office
AstraZeneca
Federal Trade Commission
Medtronic
Daiichi Sankyo
McKinsey
Chubb
Healthtrust
Baxter

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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