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Serving hundreds of leading biopharmaceutical companies globally:

AstraZeneca
Cipla
Fuji
Daiichi Sankyo
Argus Health
Covington
Healthtrust
Mallinckrodt
Chinese Patent Office

Generated: April 19, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,807,572

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Summary for Patent: 5,807,572
Title: Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
Abstract:Disclosed are multivesicular liposomes containing biologically active substances, the multivesicular liposomes having defined size distribution, adjustable average size, adjustable internal chamber size and number, and a modulated rate of the biologically active substance in contrast to the previous art. The process comprises dissolving a lipid component in volatile organic solvents, adding an immiscible aqueous component containing at least one biologically active substance to be encapsulated, and adding to either or both the organic solvents and the lipid component, a hydrochloride effective to control the release rate of the biologically active substance from the multivesicular liposome, making a water-in-oil emulsion from the two components, immersing the emulsion into a second aqueous component, dividing the emulsion into small solvent spherules which contain even smaller aqueous chambers, and then removing the solvents to give an aqueous suspension of multivesicular liposomes encapsulating biologically active substances.
Inventor(s): Kim; Sinil (Solana Beach, CA), Howell; Stephen B. (Del Mar, CA)
Assignee: DepoTech Corporation (La Jolla, CA)
Application Number:08/473,019
Patent Claim Types:
see list of patent claims
Dosage form; Process; Device;

Drugs Protected by US Patent 5,807,572

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 5,807,572

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Finland 95439 ➤ Try a Free Trial
Finland 880841 ➤ Try a Free Trial
Canada 1323568 ➤ Try a Free Trial
Germany 3879987 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

QuintilesIMS
Deloitte
Johnson and Johnson
Queensland Health
Medtronic
Fish and Richardson
Chubb
Express Scripts
Healthtrust

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