Details for Patent: 5,798,091

Summary for Patent: 5,798,091

Title:	Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
Abstract:	A gas emulsion forming composition comprising a dry, hollow, particulate, approximately microspherical material permeated with a gas or gas mixture, which upon dissolution in aqueous liquid forms a gas emulsion comprising a plurality of bubbles surrounded by a layer of at least a first and a second surfactant, wherein the first surfactant consists essentially of a phospholipid or mixture of phospholipids having at least one acyl chain which comprises at least 10 carbon atoms, and comprising at least about 5% w/w of total surfactant, and wherein the second surfactant may or may not be a phospholipid and is more water soluble than the first surfactant; kits for preparing such microbubbles; and methods for using such microbubbles as contrast agents.
Inventor(s):	Leo A. Trevino, Ernest George Schutt, David H. Klein, Thomas E. Tarara, Jeffry G. Weers, Alexey Kabalnov
Assignee:	PHOTOGEN TECHNOLOGIES Inc , TARGESON Inc
Application Number:	US08/395,680
Patent Claim Types: see list of patent claims	Use; Composition;

Drugs Protected by US Patent 5,798,091

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate

International Family Members for US Patent 5,798,091

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	281183
Australia	4922196
Australia	5199701
Australia	694135
Australia	731099