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Details for Patent: 5,785,989

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Summary for Patent: 5,785,989

Title: Compositions and methods of manufacturing of oral dissolvable medicaments
Abstract:Compositions and methods of manufacture for producing a medicament composition capable of absorption through the mucosal tissues of the mouth, pharynx, and esophagus. The present invention relates to such compositions and methods which are useful in administering lipophilic and nonlipophilic drugs in a dose-to-effect manner such that sufficient drug is administered to produce precisely a desired effect. The invention also relates to a manufacturing technique that enables a therapeutic agent or drug to be incorporated into a flavored dissolvable matrix. An appliance or holder is preferably attached to the dissolvable matrix. Employing the present invention the drug may be introduced into the patient's bloodstream almost as fast as through injection, and much faster than using the oral administration route, while avoiding the negative aspects of both of these methods. The present invention achieves these advantages by incorporating the drug into a carbohydrate, fat, protein, wax, or other dissolvable matrix composition. The dissolvable matrix may include permeation enhancers to increase the drug absorption by the mucosal tissues of the mouth. The matrix composition may also include pH buffering agents to modify the salival pH thereby increasing the absorption of the drug through the mucosal tissues.
Inventor(s): Stanley; Theodore H. (Salt Lake City, UT), Hague; Brian (West Valley City, UT)
Assignee: University Utah Research Foundation (Salt Lake City, UT)
Application Number:08/822,560
Patent Claim Types:
see list of patent claims
Dosage form; Delivery; Formulation;
Patent Metrics:
Source: PatentQuant.com
Field: Not categorized
Back Citations: 15th percentile
Forward Citations: 6th percentile

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Premature patent expiration for: 5,785,989

Expiration due to failure to pay maintenance fee

Patent Number Expiration Date
5,785,989 July 28, 2010

International Patent Family for Patent: 5,785,989

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria116131► subscribe
Austria129148► subscribe
Austria138562► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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