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Serving leading biopharmaceutical companies globally:

Federal Trade Commission
Express Scripts
Argus Health
US Department of Justice
Farmers Insurance
Accenture
Merck
McKesson
Harvard Business School
Mallinckrodt

Generated: February 19, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,770,599

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Summary for Patent: 5,770,599
Title: Quinazoline derivatives
Abstract:The invention concerns quinazoline derivatives of the formula I ##STR1## wherein n is 1, 2 or 3 and each R.sup.2 is independently halogeno, trifluoromethyl or (1-4C)alkyl; R.sup.3 is (1-4C)alkoxy; and R.sup.1 is di-[(1-4C)alkyl]amino-(2-4C)alkoxy, pyrrolidin-1-yl-(2-4C)alkoxy, piperidino-(2-4C)alkoxy, morpholino-(2-4C)alkoxy, piperazin-1-yl-(2-4C)alkoxy, 4-(1-4C)alkylpiperazin-1-yl-(2-4C)alkoxy, imidazol-1-yl-(2-4C)alkoxy, di-[(1-4C)alkoxy-(2-4C)alkyl]amino-(2-4C)alkoxy, thiamorpholino-(2-4C)alkoxy, 1-oxothiamorpholino-(2-4C)alkoxy or 1,1-dioxothiamorpholino-(2-4C)alkoxy, and wherein any of the above-mentioned R.sup.1 substituents comprising a CH.sub.2 (methylene) group which is not attached to a N or O atom optionally bears on said CH.sub.2 group a hydroxy substituent; or pharmaceutically-acceptable salts thereof; processes for their preparation, pharmaceutical compositions containing them, and the use of the receptor tyrosine kinase inhibitory properties of the compounds in the treatment of proliferative disease such as cancer.
Inventor(s): Gibson; Kieth Hopkinson (Macclesfield, GB)
Assignee: Zeneca Limited (London, GB)
Application Number:08/638,331
Patent Claim Types:
see list of patent claims
Compound; Process; Composition; Use;

Drugs Protected by US Patent 5,770,599

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 5,770,599

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9508538Apr 27, 1995

International Patents Family Members for US Patent 5,770,599

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Brazil 9608082 ➤ Sign Up
Canada 2215732 ➤ Sign Up
China 1182421 ➤ Sign Up
China 1100046 ➤ Sign Up
Czech Republic 9703396 ➤ Sign Up
Czech Republic 288489 ➤ Sign Up
Germany 69611361 ➤ Sign Up
Germany 122009000076 ➤ Sign Up
Denmark 0823900 ➤ Sign Up
Estonia 9700252 ➤ Sign Up
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

McKinsey
Teva
Fuji
US Army
Covington
Johnson and Johnson
Baxter
Express Scripts
Cerilliant

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