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Fish and Richardson
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Harvard Business School

Generated: April 26, 2018

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Details for Patent: 5,703,017

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Summary for Patent: 5,703,017
Title: 3-(Het) arylcarboxylic acid derivatives, their preparation and intermediates for their preparation
Abstract:3-(Het)arylcarboxylic acid derivatives of the formula I ##STR1## where R is formyl, CO.sub.2 H or a radical hydrolyzable to COOH and the other substituents have the following meanings: R.sup.2 and R.sup.3 are each halogen, alkyl, haloalkyl, alkoxy, haloalkoxy or alkylthio; X is nitrogen or CR.sup.14, where R.sup.14 is hydrogen or, together with R.sup.3, forms an alkylene or alkenylene chain, in each of which a methylene group is replaced by oxygen; R.sup.4 is phenyl or naphthyl, each of which is unsubstituted or substituted or an unsubstituted or substituted five-membered or six-membered heteroaromatic structure containing one to three nitrogen atoms or one sulfur or oxygen atom; R.sup.5 is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, haloalkyl, alkoxyalkyl, alkylthioalkyl or phenyl; R.sup.6 is C.sub.1 -C.sub.8 -alkyl, C.sub.3 -C.sub.6 -alkenyl, C.sub.3 -C.sub.6 -alkynyl or C.sub.3 -C.sub.4 -cyclo-alkyl, each of which may be mono- or polysubstituted; Y is sulfur, oxygen or a single bond; and Z is sulfur or oxygen; with the proviso that R.sup.6 is not unsubstituted C.sub.1 -C.sub.4 -alkyl when R.sup.4 is unsubstituted phenyl, Z is oxygen and simultaneously R.sup.5 is methyl or hydrogen.
Inventor(s): Baumann; Ernst (Dudenhofen, DE), Rheinheimer; Joachim (Ludwigshafen, DE), Vogelbacher; Uwe Josef (Ludwigshafen, DE), Bratz; Matthias (Speyer, DE), Theobald; Hans (Limburgerhof, DE), Gerber; Matthias (Limburgerhof, DE), Westphalen; Karl-Otto (Speyer, DE), Walter; Helmut (Obrigheim, DE), Rademacher; Wilhelm (Limburgerhof, DE)
Assignee: BASF Aktiengesellschaft (Ludwigshafen, DE)
Application Number:08/537,843
Patent Claim Types:
see list of patent claims
Compound; Use; Process;

Drugs Protected by US Patent 5,703,017

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 5,703,017

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
GermanyP 43 13 412.2Apr 23, 1993
PCT Information
PCT FiledApril 13, 1994PCT Application Number:PCT/EP94/01141
PCT Publication Date:November 10, 1994PCT Publication Number: WO94/25442

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