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Details for Patent: 5,691,374

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Patent 5,691,374 protects VIOXX and is included in two NDAs.

Protection for VIOXX has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

This patent has ten patent family members in ten countries.

This patent has expired prematurely due to non-payment of maintenance fees. See details below.

Summary for Patent: 5,691,374

Title: Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors
Abstract:The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.
Inventor(s): Black; Cameron (Point Claire, CA), Grimm; Erich (Baie D'Urfe, CA), Wang; Zhaoyin (Pierrefonds, CA), Leger; Serge (Dollard des Ormeaux, CA)
Assignee: Merck Frosst Canada Inc. (Kirkland, CA)
Application Number:08/443,620
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
TABLET;ORAL021042-001May 20, 1999DISCNNo5,691,374*PEDNov 18, 2015
TABLET;ORAL021042-002May 20, 1999DISCNNo5,691,374*PEDNov 18, 2015
TABLET;ORAL021042-003Feb 25, 2000DISCNNo5,691,374*PEDNov 18, 2015
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Premature patent expiration for: 5,691,374

Expiration due to failure to pay maintenance fee

Patent Number Expiration Date
5,691,374 November 25, 2009

International Patent Family for Patent: 5,691,374

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.