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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Medtronic
Federal Trade Commission
US Army
Harvard Business School
Argus Health
US Department of Justice
Cantor Fitzgerald
Merck

Generated: April 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,688,801

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Summary for Patent: 5,688,801
Title: Method of inhibiting neurotransmitter activity using microencapsulated 3-piperidiny2-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
Abstract:A pharmaceutical composition comprising a biodegradable and biocompatible composition comprising a 1,2 benzazole within a polymeric matrix. The 1,2 benzazole composition, pharmaceutically acceptable acid addition salts thereof, are potent antagonists of a series of neurotransmitters, particularly serotonin and dopamine. A method of inhibiting both serotonergic overactivity and dopaminergic overstimulation in animals is provided by administration of a biodegradable and biocompatible microparticle composition comprising a 1,2 benzazole or a pharmaceutically acceptable acid addition salt thereof. A method of treating warm blooded animals suffering from psychotic disorders, and a method of preparing the biodegradable and biocompatible composition are also described.
Inventor(s): Mesens; Jean (Wechelderzande, BE), Rickey; Michael E. (Loveland, OH), Atkins; Thomas J. (Cincinnati, OH)
Assignee: Janssen Pharmaceutica (BE) Alkermes Controlled Therapeutics Inc. II (MA)
Application Number:08/403,432
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;

Drugs Protected by US Patent 5,688,801

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

UBS
Healthtrust
Deloitte
Chubb
Fish and Richardson
McKinsey
Baxter
Medtronic
AstraZeneca

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