|Title:||Dry mix formulation for bisphosphonic acids|
|Abstract:||Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease.|
|Inventor(s):||Bechard; Simon R. (Quebec, CA), Kramer; Kenneth A. (Green Lane, PA), Katdare; Ashok V. (Norristown, PA)|
|Assignee:||Merck & Co., Inc. (Rahway, NJ)|
Patent Claim Types:|
see list of patent claims
|Dosage form; Process; Composition;|
|Patent Number||Expiration Date|
|5,681,590||October 28, 2009|
|PCT Filed||November 17, 1993||PCT Application Number:||PCT/US93/11172|
|PCT Publication Date:||June 09, 1994||PCT Publication Number:||WO94/12200|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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