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Generated: September 23, 2017

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Title: Dual control sustained release drug delivery systems and methods for preparing same
Abstract:The present invention pertains to a dual control sustained release drug delivery system which comprises a core and a porous coating layer over the core, wherein the coated core comprises (A) a core comprising in percentages by weight of the core composition (a) a medicament present in an amount from about 60% to about 90%; (b) an edible material having a melting point from about 25.degree. C. to about 100.degree. C. selected from the group consisting of (i) fatty acids having an iodine value from about 1 to about 10, (ii) natural waxes, (iii) synthetic waxes, and (iv) mixtures thereof, present in an amount from about 5% to about 40%; and (B) a porous coating layer over the core comprising in percentages by weight of the coating layer composition (a) a pH-independent water-insoluble polymer present in an amount from about 40% to about 80%; and (b) a water-soluble film forming polymer present in an amount from about 20% to about 60%.
Inventor(s): Khan; Sadath U. (Randolph, NJ), Ying; Phyllis (Morristown, NJ), Nesbitt; Russell U. (Somerville, NJ), Fawzi; Mahdi B. (Flanders, NJ), Weiss; Jay (East Brunswick, NJ)
Assignee: Warner-Lambert Company (Morris Plains, NJ)
Application Number:08/476,490
Patent Claim Types:
see list of patent claims
Delivery; Composition; Process; Dosage form;

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Serving 500+ biopharmaceutical companies globally:

Daiichi Sankyo
Boehringer Ingelheim
Federal Trade Commission
Fish and Richardson
Cantor Fitzgerald
US Department of Justice

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