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|Title:||Process for removing bile salts from a patient and compositions therefor|
|Abstract:||A method for removing bile salts from a patient by ion exchange by administering to the patient a therapeutically effective amount of one or more highly crosslinked polymers characterized by a repeat unit having the formula ##STR1## or copolymer thereof, where n is an integer; R.sup.1 is H or a C.sub.1 -C.sub.8 alkyl group; M is ##STR2## or --Z--R.sup.2 ; Z is O, NR.sup.3, S, or (CH.sub.2).sub.m ; m=0-10; R.sup.3 is H or a C.sub.1 -C.sub.8 alkyl group; and R.sup.2 is ##STR3## where p=0-10, and each R.sup.4, R.sup.5, and R.sup.6, independently, is H, a C.sub.1 -C.sub.8 alkyl group, or an aryl group, the polymers being non-toxic and stable once ingested.|
|Inventor(s):||Mandeville, III; W. Harry (Lynnfield, MA), Holmes-Farley; Stephen R. (Arlington, MA)|
|Assignee:||GelTex Pharmaceuticals, Inc. (Waltham, MA)|
Patent Claim Types:|
see list of patent claims
|Use; Compound; Composition;|
|Patent Number||Expiration Date|
|5,624,963||April 29, 2001|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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