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Serving hundreds of leading biopharmaceutical companies globally:

McKesson
Dow
UBS
Baxter
Covington
Cantor Fitzgerald
Chinese Patent Office
Mallinckrodt
Queensland Health

Generated: April 23, 2018

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Details for Patent: 5,616,582

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Summary for Patent: 5,616,582
Title: Quinazoline derivatives as anti-proliferative agents
Abstract:The invention concerns quinazoline derivatives of the formula I ##STR1## wherein m is 1, 2 or 3 and each R.sup.1 includes hydroxy, amino, carboxy, carbamoyl, ureido, (1-4C)alkoxycarbonyl, N-(1-4C)alkylcarbamoyl, N,N-di-[(1-4C)alkyl]carbamoyl, hydroxyamino, (1-4C)alkoxyamino, (2-4C)alkanoyloxyamino, trifluoromethoxy, (1-4C)alkyl, (1-4C)alkoxy and (1-3C)alkylenedioxy; n is 1 or 2 and each R.sup.2 includes hydrogen, hydroxy, halogeno, trifluoromethyl, amino, nitro, cyano and (1-4C)alkyl; or a pharmaceutically-acceptable salt thereof; processes for their preparation; pharmaceutical compositions containing them; and the use of the receptor tyrosine kinase inhibitory properties of the compounds in the treatment of cancer.
Inventor(s): Barker; Andrew J. (Macclesfield, GB2)
Assignee: Zeneca Limited (London, GB)
Application Number:08/490,666
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 5,616,582

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 5,616,582

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9201095Jan 20, 1992
United Kingdom9213572Jun 26, 1992
United Kingdom9223735Nov 12, 1992

International Patents Family Members for US Patent 5,616,582

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 130000 ➤ Try a Free Trial
Australia 3101093 ➤ Try a Free Trial
Australia 661533 ➤ Try a Free Trial
Canada 2086968 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

McKinsey
Federal Trade Commission
Argus Health
Accenture
Daiichi Sankyo
Teva
AstraZeneca
UBS
Cerilliant

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