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Generated: August 20, 2017

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Title: Method of preventing NMDA receptor-mediated neuronal damage
Abstract:Disclosed is a method for reducing non-ischemic NMDA receptor-mediated neuronal damage in a mammal by administering to the mammal a compound of the formula shown in FIG. 1 (or a physiologically-acceptable salt thereof), wherein R.sub.1 includes an amino group, R.sub.2 -R.sub.17 are independently H or a short chain aliphatic group comprising 1-5 carbons, and R.sub.4 and R.sub.10 also may (independently) be a halogen or an acyl group. Also disclosed is a screen for antagonists of NMDA receptor mediated neurotoxicity which have an enhanced prospect for being clinically tolerated and selective against such neurotoxicity.
Inventor(s): Lipton; Stuart A. (Newton, MA)
Assignee: Children's Medical Center Corporation (Boston, MA)
Application Number:08/419,672
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Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia6351698► Subscribe
Canada2143752► Subscribe
Germany69027026► Subscribe
Germany69229598► Subscribe
Germany69330387► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving 500+ biopharmaceutical companies globally:

Cantor Fitzgerald
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