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Last Updated: April 18, 2024

Details for Patent: 5,614,560

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Summary for Patent: 5,614,560

Title:	Method of preventing NMDA receptor-mediated neuronal damage
Abstract:	Disclosed is a method for reducing non-ischemic NMDA receptor-mediated neuronal damage in a mammal by administering to the mammal a compound of the formula shown in FIG. 1 (or a physiologically-acceptable salt thereof), wherein R.sub.1 includes an amino group, R.sub.2 -R.sub.17 are independently H or a short chain aliphatic group comprising 1-5 carbons, and R.sub.4 and R.sub.10 also may (independently) be a halogen or an acyl group. Also disclosed is a screen for antagonists of NMDA receptor mediated neurotoxicity which have an enhanced prospect for being clinically tolerated and selective against such neurotoxicity.
Inventor(s):	Lipton; Stuart A. (Newton, MA)
Assignee:	Children's Medical Center Corporation (Boston, MA)
Application Number:	08/419,672
Patent Claim Types: see list of patent claims	Use;

Drugs Protected by US Patent 5,614,560

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	182076	⤷ Try a Trial
Austria	202474	⤷ Try a Trial
Austria	330606	⤷ Try a Trial
Australia	4847693	⤷ Try a Trial
Australia	5348194	⤷ Try a Trial
Australia	5419690	⤷ Try a Trial
Australia	6351698	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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