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Last Updated: April 25, 2024

Details for Patent: 5,591,731

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Summary for Patent: 5,591,731

Title:	Crystalline amifostine compositions
Abstract:	The present invention relates to a sterile, stable vacuum dried crystalline amifostine composition and, optionally, pharmaceutically acceptable excipient(s). Typically, the crystalline compositions of the present invention exhibit enhanced stability at temperatures ranging from about 4.degree. C. to about ambient temperature for a period of at least 2 years relative to existing solid vacuum dried amorphous amifostine preparations. The reconstituted compositions of the present invention are suitable for administration to humans as a radio- or chemoprotecting agent.
Inventor(s):	Kennedy; Paul E. (Phoenixville, PA), Rajewski; Roger A. (Lawrence, KS), Baldoni; John M. (Glenmore, PA)
Assignee:	U.S. Bioscience, Inc. (West Conshohocken, PA)
Application Number:	08/389,386
Patent Claim Types: see list of patent claims	Compound; Dosage form; Composition; Formulation;

Drugs Protected by US Patent 5,591,731

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 5,591,731

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	261729	⤷ Try a Trial
Australia	4796693	⤷ Try a Trial
Australia	681858	⤷ Try a Trial
Canada	2120133	⤷ Try a Trial
China	1070370	⤷ Try a Trial
China	1092980	⤷ Try a Trial
China	1146428	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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