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Details for Patent: 5,591,731

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Summary for Patent: 5,591,731

Title: Crystalline amifostine compositions
Abstract:The present invention relates to a sterile, stable vacuum dried crystalline amifostine composition and, optionally, pharmaceutically acceptable excipient(s). Typically, the crystalline compositions of the present invention exhibit enhanced stability at temperatures ranging from about 4.degree. C. to about ambient temperature for a period of at least 2 years relative to existing solid vacuum dried amorphous amifostine preparations. The reconstituted compositions of the present invention are suitable for administration to humans as a radio- or chemoprotecting agent.
Inventor(s): Kennedy; Paul E. (Phoenixville, PA), Rajewski; Roger A. (Lawrence, KS), Baldoni; John M. (Glenmore, PA)
Assignee: U.S. Bioscience, Inc. (West Conshohocken, PA)
Application Number:08/389,386
Patent Claim Types:
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Compound; Dosage form; Composition; Formulation;

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International Patent Family for Patent: 5,591,731

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office1243272<disabled in preview>
Czech Republic9500230<disabled in preview>
Czech Republic284417<disabled in preview>
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
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