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|Title:||Persistent gaseous bubbles as ultrasound contrast media|
|Abstract:||Disclosed herein are agents for enhancing the contrast in an ultrasound image. These agents are extremely small bubbles, or "microbubbles," comprised of specially selected gases. The microbubbles described herein exhibit long life spans in solution and may be produced at a size small enough to traverse the lungs, thus enabling improved ultrasound imaging of the cardiovascular system and other vital organs. Also disclosed herein is a method for selecting gases from which contrast agents may be produced. The method is based on calculations using inherent physical properties of gases and describes a means to associate the properties of a gas with the time for dissolution of a microbubble comprised of the gas.|
|Inventor(s):||Quay; Steven C. (Los Angeles, CA)|
|Assignee:||Sonus Pharmaceuticals, Inc. (Bothell, WA)|
Patent Claim Types:|
see list of patent claims
|Composition; Dosage form; Delivery; Compound;|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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