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Serving hundreds of leading biopharmaceutical companies globally:

Teva
Daiichi Sankyo
Mallinckrodt
McKesson
Julphar
QuintilesIMS
Queensland Health
Healthtrust
Argus Health

Generated: May 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,545,644

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Summary for Patent: 5,545,644
Title: Indole derivatives
Abstract:Compounds of the formula ##STR1## wherein n is 0, 1, or 2; X is hydrogen, chlorine, bromine or iodine; R.sub.1 is hydrogen; R.sub.3 is selected from hydrogen and C.sub.1 to C.sub.6 linear or branched alkyl; and R.sub.2 is as defined in the specification and the pharmaceutically acceptable salts thereof are useful psychotherapeutics and are potent serotonin (5-HT.sub.1) agonists and may be used in the treatment of depression, anxiety, eating disorders, obesity, drug abuse, cluster headache, migraine, pain, chronic paroxysmal hemicrania and headache associated with vascular disorders, and other disorders arising from deficient serotonergic neurotransmission. The compounds can also be used as centrally acting antihypertensives and vasodilators. A process for forming indoles by transition metal catalyzed cyclization of a dihalogenated intermediate is also disclosed.
Inventor(s): Macor; John E. (New York, NY), Wythes; Martin J. (New York, NY)
Assignee: Pfizer Inc. (New York, NY)
Application Number:08/466,644
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 5,545,644

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

QuintilesIMS
Merck
Mallinckrodt
Baxter
Julphar
Chinese Patent Office
Fish and Richardson
Covington
Teva

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