Details for Patent: 5,488,150
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Summary for Patent: 5,488,150
Title: | Crystals of N-(trans-4-isopropylcyclohexycarbonyl)-D-phenylalanine and methods for preparing them |
Abstract: | Stable crystals of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine may be produced by treating this compound with a solvent at a temperature of at least 10.degree. C. and forming crystals in the solvent at a temperature of at least 10.degree. C. For example, crystals may be formed by crystallization out of solution, or may be formed from solid particles of the compound suspended in a solvent. Crystals formed in this way have different melting point, infra red spectrum and X-ray diffraction patterns from previously known forms of the compound and have enhanced processability, eg. stability to grinding. |
Inventor(s): | Sumikawa; Michito (Kawasaki, JP), Koguchi; Yoshihito (Kawasaki, JP), Ohgane; Takao (Kawasaki, JP), Irie; Yasuo (Kawasaki, JP), Takahashi; Satoji (Yottukaichi, JP) |
Assignee: | Ajinomoto Co., Inc. (Tokyo, JP) |
Application Number: | 08/166,144 |
Patent Claim Types: see list of patent claims | Use; Formulation; Composition; |
Drugs Protected by US Patent 5,488,150
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Foreign Priority and PCT Information for Patent: 5,488,150
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