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Serving leading biopharmaceutical companies globally:

Fish and Richardson
Argus Health
Chinese Patent Office
Harvard Business School
US Department of Justice
Healthtrust
Julphar
Dow
Cerilliant
Accenture

Generated: January 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,478,820

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Summary for Patent: 5,478,820
Title: Antibiotic compounds
Abstract:The present invention relates to carbapenems and provides a compound of the formula (I): ##STR1## or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof wherein: R.sup.1 is 1-hydroxyethyl, 1-fluoroethyl or hydroxymethyl; R.sup.2 is hydrogen or C.sub.1-4 alkyl; R.sup.3 is hydrogen or C.sub.1-4 alkyl; R.sup.4 and R.sup.5 are the same or different and are selected from hydrogen, halo, cyano, C.sub.1-4 alkyl, nitro, hydroxy, carboxy, C.sub.1-4 alkoxy, C.sub.1-4 alkoxycarbonyl, aminosulphonyl, C.sub.1-4 alkylaminosulphonyl, di-C.sub.1-4 alkylaminosulphonyl, carbamoyl, C.sub.1-4 alkylcarbamoyl, di-C.sub.1-4 alkylcarbamoyl, trifluoromethyl, sulphonic acid, amino, C.sub.1-4 alkylamino, di-C.sub.1-4 alkylamino, C.sub.1-4 alkanoylamino, C.sub.1-4 alkanoyl(N-C.sub.1-4 alkyl)amino, C.sub.1-4 alkanesulphonamido and C.sub.1-4 alkylS(O).sub.n -- wherein n is zero, one or two: with the proviso that there is no hydroxy or carboxy substituent in a position ortho to the --NR.sup.2 --. Processes for their preparation, intermediates in their preparation, their use as therapeutic agents and pharmaceutical compositions containing them.
Inventor(s): Betts; Michael J. (Wilmslow, GB2), Davies; Gareth M. (Macclesfield, GB2), Swain; Michael L. (Stockport, GB2)
Assignee: Zeneca Ltd. (London, GB2)
Application Number:08/129,056
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 5,478,820

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 5,478,820

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9202298Feb 04, 1992
PCT Information
PCT FiledFebruary 02, 1993PCT Application Number:PCT/GB93/00217
PCT Publication Date:August 05, 1993PCT Publication Number: WO93/15078

International Patents Family Members for US Patent 5,478,820

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Israel 104588 ➤ Subscribe
Hungary T64764 ➤ Subscribe
Hungary 9302777 ➤ Subscribe
Hungary 211840 ➤ Subscribe
Hungary T66514 ➤ Subscribe
Hungary 213675 ➤ Subscribe
Croatia P930103 ➤ Subscribe
Hong Kong 1013998 ➤ Subscribe
Germany 69322007 ➤ Subscribe
Denmark 0579826 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Teva
QuintilesIMS
Cantor Fitzgerald
Argus Health
Colorcon
Daiichi Sankyo
Cipla
Federal Trade Commission

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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