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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Farmers Insurance
Federal Trade Commission

Generated: October 22, 2017

DrugPatentWatch Database Preview

Details for Patent: 5,478,820

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Summary for Patent: 5,478,820

Title: Antibiotic compounds
Abstract:The present invention relates to carbapenems and provides a compound of the formula (I): ##STR1## or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof wherein: R.sup.1 is 1-hydroxyethyl, 1-fluoroethyl or hydroxymethyl; R.sup.2 is hydrogen or C.sub.1-4 alkyl; R.sup.3 is hydrogen or C.sub.1-4 alkyl; R.sup.4 and R.sup.5 are the same or different and are selected from hydrogen, halo, cyano, C.sub.1-4 alkyl, nitro, hydroxy, carboxy, C.sub.1-4 alkoxy, C.sub.1-4 alkoxycarbonyl, aminosulphonyl, C.sub.1-4 alkylaminosulphonyl, di-C.sub.1-4 alkylaminosulphonyl, carbamoyl, C.sub.1-4 alkylcarbamoyl, di-C.sub.1-4 alkylcarbamoyl, trifluoromethyl, sulphonic acid, amino, C.sub.1-4 alkylamino, di-C.sub.1-4 alkylamino, C.sub.1-4 alkanoylamino, C.sub.1-4 alkanoyl(N-C.sub.1-4 alkyl)amino, C.sub.1-4 alkanesulphonamido and C.sub.1-4 alkylS(O).sub.n -- wherein n is zero, one or two: with the proviso that there is no hydroxy or carboxy substituent in a position ortho to the --NR.sup.2 --. Processes for their preparation, intermediates in their preparation, their use as therapeutic agents and pharmaceutical compositions containing them.
Inventor(s): Betts; Michael J. (Wilmslow, GB2), Davies; Gareth M. (Macclesfield, GB2), Swain; Michael L. (Stockport, GB2)
Assignee: Zeneca Ltd. (London, GB2)
Application Number:08/129,056
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

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Foreign Priority and PCT Information for Patent: 5,478,820

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9202298Feb 04, 1992
PCT Information
PCT FiledFebruary 02, 1993PCT Application Number:PCT/GB93/00217
PCT Publication Date:August 05, 1993PCT Publication Number: WO93/15078

International Patent Family for Patent: 5,478,820

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Israel104588► Subscribe
HungaryT64764► Subscribe
Hungary9302777► Subscribe
Hungary211840► Subscribe
HungaryT66514► Subscribe
Hungary213675► Subscribe
CroatiaP930103► Subscribe
Hong Kong1013998► Subscribe
Germany69322007► Subscribe
Denmark0579826► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Fish and Richardson
Argus Health
Johnson and Johnson
US Army
Chinese Patent Office

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