Details for Patent: 5,447,926

Summary for Patent: 5,447,926

Title:	Quinolone carboxylic acid derivatives
Abstract:	A quinolone carboxylic acid derivative having the following formula (1), ##STR1## wherein R1 is a hydrogen atom, an alkyl group, an aralkyl group, an ester residual group which can be hydrolyzed in living bodies, R2 is a hydrogen atom or an amino group which may be substituted by one or two lower alkyl groups, X is a hydrogen atom or a halogen atom, Y is CH2, O, S, SO, SO2, or N--R3, wherein R3 is a hydrogen atom or a lower alkyl group, and Z is an oxygen atom or two hydrogen atoms; or a salt thereof; and an antimicrobial agent comprising the same. The compound exhibits a superior antimicrobial activity, especially against gram positive microorganisms, and is thus useful for the treatments and prevention of various infectious diseases in clinics.
Inventor(s):	Fujiko Konno, Akihiro Shibata, Hideaki Matsuda, Takemitsu Asaoka, Ryuichi Kawahara, Naokata Taido, Tasdayuki Kuraishi, Sunao Takeda
Assignee:	Biomedix Co Ltd , Bausch and Lomb Inc
Application Number:	US08/305,977
Patent Claim Types: see list of patent claims	Use; Composition;

Drugs Protected by US Patent 5,447,926

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate

Foreign Priority and PCT Information for Patent: 5,447,926

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Japan	2-191339	Jul 19, 1990
Japan	3-079774	Apr 12, 1991

International Family Members for US Patent 5,447,926

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	128707
Canada	2065846
Germany	69113604
Denmark	0493608
European Patent Office	0493608
Spain	2080327