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Generated: November 24, 2017

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Details for Patent: 5,431,900

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Summary for Patent: 5,431,900

Title: Ester-substituted diaminedithiols and radiolabeled complexes thereof
Abstract:Radiopharmaceuticals consisting essentially of a lipophilic, charge neutral radionuclide complex of a diaminedithiol ligand having 1-4 ester groups of the formula --A--COOR where A is a straight or branched chain alkylene of 0-10 carbon atoms and R is an alkyl group of 1-10 carbon atoms are useful in radioimaging brain perfusion in primates. Ester-substituted diaminedithiols in sterile, pharmaceutically acceptable form, and kits of the diaminedithiols and sterile, non-pyrogenic reducing agents for reducing preselected radionuclides are also provided. Technetium-99m is a preferred radionuclide.
Inventor(s): Bergstein; Paul L. (Norwood, MA), Cheesman; Edward H. (Townsend, MA), Watson; Alan D. (Andover, MA)
Assignee: The Du Pont Merck Pharmaceutical Company (Wilmington, DE)
Application Number:08/139,894
Patent Claim Types:
see list of patent claims
Compound; Device;

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International Patent Family for Patent: 5,431,900

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office0279417► Subscribe95C0005Belgium► Subscribe
Spain2042609► Subscribe
Denmark175089► Subscribe
Denmark81688► Subscribe
Germany3871173► Subscribe
Germany19475010► Subscribe
Greece3004986► Subscribe
Hong Kong66292► Subscribe
Ireland880431► Subscribe
Canada1271195► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Colorcon
Federal Trade Commission
McKesson
Queensland Health
Accenture
Dow
Chubb
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Moodys
Fuji

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