Last Updated: August 3, 2026

Details for Patent: 5,431,900

Name: Drug Patent Intelligence for US Patent 5431900
Creator: DrugPatentWatch
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Summary for Patent: 5,431,900

Title:	Ester-substituted diaminedithiols and radiolabeled complexes thereof
Abstract:	Radiopharmaceuticals consisting essentially of a lipophilic, charge neutral radionuclide complex of a diaminedithiol ligand having 1-4 ester groups of the formula -A-COOR where A is a straight or branched chain alkylene of 0-10 carbon atoms and R is an alkyl group of 1-10 carbon atoms are useful in radioimaging brain perfusion in primates. Ester-substituted diaminedithiols in sterile, pharmaceutically acceptable form, and kits of the diaminedithiols and sterile, non-pyrogenic reducing agents for reducing preselected radionuclides are also provided. Technetium-99m is a preferred radionuclide.
Inventor(s):	Paul L. Bergstein, Edward H. Cheesman, Alan D. Watson
Assignee:	Lantheus Medical Imaging Inc , ACP Lantern Acquisition Inc
Application Number:	US08/139,894
Patent Claim Types: see list of patent claims	Compound; Device;

Drugs Protected by US Patent 5,431,900

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 5,431,900

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	0279417	⤷ Start Trial	95C0005	Belgium	⤷ Start Trial
Austria	76401	⤷ Start Trial
Australia	1174888	⤷ Start Trial
Australia	614276	⤷ Start Trial
Canada	1271195	⤷ Start Trial
Germany	19475010	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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