Tablets with controlled-rate release of active substances
Tablets with zero order controlled-rate of release of the active substances, consisting of a core of defined geometrical form containing the active substance, polymer substances which swell on contact with aqueous liquids and polymer substances with gelling properties, and a support applied to said core to partly cover its surface, the support consisting of polymer substances which are slowly soluble and/or slowly gellable in aqueous liquids, plasticizing substances, and possibly substances with an adjuvant function.
Conte; Ubaldo (Busto Arsizio, IT), La Manna; Aldo (Pavia, IT), Colombo; Paolo (Pavia, IT)
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