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Last Updated: October 30, 2020

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Details for Patent: 5,387,603

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Summary for Patent: 5,387,603
Title: 1,5,7-trisubstituted indoline compounds and salts thereof
Abstract:Indoline compounds represented by the formula: ##STR1## wherein R represents a saturated or unsaturated aliphatic acyl group which may have one or more halogen atoms, a hydroxy group, a lower alkoxy group, a carboxy group, a lower alkoxycarbonyl group, a cycloalkyl group or an aryl group as substituents; a hydroxyalkyl group; an aliphatic acyloxyalkyl group; a lower alkyl group having a lower alkoxy group, a carboxy group, a lower alkoxycarbonyl group, an aryl substituted lower alkoxycarbonyl group, a carbamoyl group, a mono- or dialkyl substituted carbamoyl group or a cyano group as substituents; an aromatic acyl group which may have one or more halogen atoms as substituents; a furoyl group or a pyridylcarbonyl group; R.sup.1 represents a lower alkyl group which may have one or more halogen atoms or an aryl group as substituents; and pharmaceutically acceptable salts thereof, exhibit a selective suppressive action on urethral contractions, and thus are useful as therapeutic agents for the treatment of dysuria with less hypotension including postural hypotension.
Inventor(s): Kitazawa; Makio (Nagano, JP), Ban; Masaaki (Nagano, JP), Okazaki; Kosuke (Nagano, JP), Ozawa; Motoyasu (Nagano, JP), Yazaki; Toshikazu (Nagano, JP), Yamagishi; Ryoichi (Nagano, JP)
Assignee: Kissei Pharmaceutical Co., Ltd. (Nagano, JP)
Application Number:08/159,624
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 5,387,603

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 5,387,603

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan4-356197Dec 02, 1992

International Family Members for US Patent 5,387,603

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