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Serving leading biopharmaceutical companies globally:

Daiichi Sankyo
Argus Health

Generated: November 22, 2017

DrugPatentWatch Database Preview

Details for Patent: 5,310,912

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Summary for Patent: 5,310,912

Title: Iodinated neuroprobe for mapping monoamine reuptake sites
Abstract:An iodinated neuroprobe is provided for mapping monoamine reuptake sites. The iodinated neuroprobe is of the formula: ##STR1## wherein R=a C.sub.n H.sub.2n+1 group where n=0-6, an alkenyl group, a monofluoroalkyl group including .sup.n F where n=18 or 19, or a .sup.m C.sub.n H.sub.2n+1 group where n=1-6 and where m=11 or 14 for at least one .sup.m C; R'=a C.sub.n H.sub.2n+1 group where n=0-6, a p-iodophenylmethyl group, a p-iodophenylethyl group, a phenylmethyl group, or a phenylethyl group; X=an isotope of F, an isotope of Cl, an isotope of Br, an isotope of I, CH.sub.3, or Sn(R".sub.1 R".sub.2 R".sub.3); R".sub.1 =a C.sub.n H.sub.2n+1 group where n=1-6, or an aryl group; R".sub.2 =a C.sub.n H.sub.2n+1 group where n=1-6, or an aryl group; R".sub.3 =a C.sub.n H.sub.2n+1 group where n=1-6, or an aryl group; and Y=H only if X is an isotope of I, or R' is a p-iodophenylmethyl group, or R' is a p-iodophenylethyl group, else Y=an isotope of I. Related analogs are also provided. Additionally, a precursor of a radiolabled neuroprobe and a kit for preparing the iodinated neuroprobe are provided.
Inventor(s): Neumeyer; John L. (Wayland, MA), Milius; Richard A. (Boston, MA), Innis; Robert B. (Hamden, CT)
Assignee: Research Biochemicals Limited Partnership (Natick, MA)
Application Number:07/841,617
Patent Claim Types:
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International Patent Family for Patent: 5,310,912

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Spain2189792► Subscribe
Germany10399020► Subscribe
Germany69332544► Subscribe
Denmark0703791► Subscribe
European Patent Office0703791► Subscribe300123Netherlands► Subscribe
European Patent Office0703791► SubscribeSPC/GB03/010United Kingdom► Subscribe
European Patent Office0703791► SubscribeCA 2003 00010Denmark► Subscribe
European Patent Office0703791► SubscribeC300123Netherlands► Subscribe
European Patent Office0703791► Subscribe03C0021France► Subscribe
European Patent Office0703791► Subscribe9/2003Austria► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

US Army
Queensland Health
Boehringer Ingelheim
Federal Trade Commission
Farmers Insurance

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